Upgrade of 400 MHz NMR Spectrometer

摘要博尔顿93-03077建议将现有的核磁共振光谱仪升级为设计更现代的双通道光谱仪。光谱仪将配置现有的质子探测探头，其X通道能力在15 N和31 P之间，以及质子探头。升级后的谱仪要求能够进行天然丰度异源相关实验，能够进行天然丰度下的碳碳相关实验，能够对水中样品进行质子二维等实验，能够获得高质量的COSY、TOCSY、ROESY和NOESY数据进行定量分析，能够进行三维NMR实验。升级后的控制台将对基本碳、氮和磷提供更高的有效灵敏度，因为伪影信号的水平将大大降低。升级的主要价值是允许进行一系列全新的实验。

Abstract Bolton 93-03077 It is proposed to upgrade an existing NMR spectrometer to a two-channel spectrometer of more modern design. The spectrometer will be configured with existing proton detection probes with X channel capability between 15N and 31P and a proton probe. The upgraded spectrometer is required to be able to perform natural abundance heteronuclear correlation experiments, to perform carbon- carbon correlation experiments at natural abundance, to perform proton two-dimensional and other experiments on samples in water, to obtain high quality COSY, TOCSY, ROESY and NOESY data for quantitative analysis and to perform three-dimensional NMR experiments. The upgraded console will offer significantly greater effective sensitivity for basic carbon, nitrogen and phosphorus since the level of artifact signals will be substantially reduced. The major value of the upgrade is to allow a range of entirely new experiments to be performed.