Acquisition of a Single Crystal X-ray Diffractometer

提供资金购买一台单晶X射线衍射仪，以便在一个以本科为主的机构开展四个跨学科的研究项目。目前，该研究所或当地大学的研究实验室都没有精炼单晶结构的能力。拟议的设备提供了与工业和外部研究机构进行合作研究的能力。 具体地说，该设备将用于：1）钛铝合金的定量分析; 2）氧化铝和磁铅石型化合物中键长和化合价的测定; 3）有机金属聚合物和刚性棒聚合物的检验; 4）聚氟亚芳基桥接聚合物的研究; 5）具有高度氟化侧链的乙烯基聚合物的探索; 6）手性膦酸酯过渡态类似物作为HIV-1蛋白酶抑制剂的研究;和7）确定pumpellyite晶体结构变化与其组成变化之间的对应关系。这些研究在开发高性能，高温合金，更好地理解在尖晶石块的晶体化学的结构/性能关系，开发工业上重要的聚合物，并建立一个合理的设计在HIV-1蛋白酶类似物的合成中的应用。 %资金用于购买一台单晶X射线衍射仪，以便在一所以本科为主的机构开展四项跨学科研究计划。目前，该研究所或当地大学的研究实验室都没有精炼单晶结构的能力。来自化学，物理，地质和材料工程系的研究人员进行了各种各样的研究，这些研究在以下方面具有应用：1）开发高性能、高温合金，2）更好地理解材料的结构/性能关系，3）开发工业上重要的聚合物，（4）建立了HIV-1蛋白酶类似物合成的合理设计。拟议的研究包括与行业和外部研究机构的合作。

Funds are provided for the purchase of a single crystal X- ray diffractometer to conduct four interdisciplinary research programs at a predominantly undergraduate institution. Currently, no capability for refining single crystal structures exists at the institution or in the research laboratories of local universities. The proposed equipment provides capabilities to conduct collaboration research with industry and outside research institutions. Specifically, the equipment is to be used in: 1) quantitative analysis of titanium aluminum alloys; 2) determination of bond lengths and valences in alumina and magnetoplumbite-type compounds; 3) examination of organometallic polymers and rigid rod polymers; 4) investigation of ployfluroarylene bridged polymers; 5) exploration of vinyl polymers having highly fluorinated side chains; 6) study of chiral phosphonate transition state analogues as inhibitors of HIV-1 protease; and 7) the determination of the correspondence between changes in the crystal structure of pumpellyite with changes in its composition. These studies have applications in the development of high-performance, high-temperature alloys, better understanding of structure/property relations of the crystal chemistry at the spinel blocks, development of industrially important polymers, and establishing a rational design in the synthesis of analogues of HIV-1 protease. %%% Funds are provided for the purchase of a single crystal X- ray diffractometer to conduct four interdisciplinary research programs at a predominantly undergraduate institution. Currently, no capability for refining single crystal structures exists at the institution or in the research laboratories of local universities. Researchers from Departments of Chemistry, Physics, Geology, and Material Engineering conduct a diverse range of studies that have applications in: 1) the development of high- performance, high-temperature alloys, 2) better understanding of structure/property relations of mate rials, 3) development of industrially important polymers, and 4) establishing a rational design in the synthesis of analogues of HIV-1 protease. The proposed research includes collaboration with industry and outside research institutions.