Functions of the activating E2fs beyond cell cycle control
Functions of the activating E2fs beyond cell cycle control
批准号:
190239
负责人:
Bremner Rod
金额:
$66.22万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-09-01 至 2014-09-01
中文摘要
E2F家族在人类癌症中起着关键作用。在某些情况下,它们可以通过促进细胞分裂来推动癌症。在其他情况下,低E2F活性促进了肿瘤的生长,但现在已经清楚了这是如何发生的。临床上有一些药物可以抑制
英文摘要
The E2f family play crucial roles in human cancer. In some cases they can drive cancer by promoting cell division. In other cases low E2f activity facilitates tumor growth, but it is now clear how this occurs. There are drugs in the clinic that inhibit
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Role of YAP and TAZ in Acute Myeloid Leukemia
-
批准号:462899
-
项目类别:Operating Grants
-
资助金额:$65.76万
-
财政年份:2022
-
负责人:Bremner Rod
-
依托单位:
Dissecting the Tumor Suppressor Function of YAP in Neural and Neuroendocrine Cancers
-
批准号:452608
-
项目类别:Operating Grants
-
资助金额:$73.84万
-
财政年份:2021
-
负责人:Bremner Rod
-
依托单位:
The Single Cell Biology of Context-Specific Responses to Loss of the RB Tumor Suppressor Gene
-
批准号:419746
-
项目类别:Operating Grants
-
资助金额:$58.41万
-
财政年份:2020
-
负责人:Bremner Rod
-
依托单位:
Resistance to established and new RET oncogene inhibitors
-
批准号:415232
-
项目类别:Operating Grants
-
资助金额:$7.29万
-
财政年份:2019
-
负责人:Bremner Rod
-
依托单位:
Opposite roles of MYCN and YAP in cancer initiation
-
批准号:357665
-
项目类别:Operating Grants
-
资助金额:$52.94万
-
财政年份:2016
-
负责人:Bremner Rod
-
依托单位:
Mechanisms regulating the outgrowth of initiated cells in the mammal
-
批准号:211145
-
项目类别:Operating Grants
-
资助金额:$77.11万
-
财政年份:2010
-
负责人:Bremner Rod
-
依托单位:
2nd Retinoblastoma Tumor Suppressor Symposium - Toronto 2011
-
批准号:208454
-
项目类别:Miscellaneous Programs
-
资助金额:$1.46万
-
财政年份:2010
-
负责人:Bremner Rod
-
依托单位:
海外基金