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Mechanisms of the tumor suppression activity of the ERK pathway

Mechanisms of the tumor suppression activity of the ERK pathway
ERK通路的肿瘤抑制活性机制
批准号:
209752
负责人:
Ferbeyre Gerardo
金额:
$57.66万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-09-01 至 2015-09-01

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中文摘要
翻译
在正常的健康生物体中,细胞增殖受到仔细的控制,致癌刺激的影响被细胞肿瘤抑制反应所中和。我们已经发现,一条以传递增殖而闻名的细胞信号通路
英文摘要
In normal healthy organisms cell proliferation is carefully controlled and the effects of oncongenic stimuli are neutralized by cellular tumor suppressor responses. We have discovered that a cellular signaling pathway known best for conveying proliferatio
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Targeting ribosomal RNA biogenesis to restore the senescence tumor suppression mechanism
Elimination of senescent cells to treat estrogen-deprivation associated disorders
Molecular mechanisms of oncogene-induced senescence
Targeting senescence cells in pancreatic cancer
  • 批准号:
    364242
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2017
  • 负责人:
    Ferbeyre Gerardo
  • 依托单位:
海外基金