Integration of Fourier Transform Nuclear Magnetic Resonance into the Undergraduate Chemistry Curriculum

本项目旨在将核磁共振理论与实践融入本科化学课程。有机化学实验室的初步实验侧重于H1、C13和NOE（核Overhauser效应）光谱的解释，以及如何利用化学位移、分裂模式、耦合常数和积分比获得的信息来阐明结构。在随后的课程和实验中，FT-NMR实验的性质和仪器操作变量将被检查，涉及反应动力学、顺磁性化合物的磁矩、分子内重排、二维方法和其他应用的问题将被研究。对没有经验的本科生进行傅里叶变换核磁共振光谱仪操作的教学正在通过录像带加强，录像带描述了磁铁周围的安全，样品制备，仪器设置以及各种实验的逐步计算机命令，数据采集和处理，以及光谱的呈现。此外，该部门正在开展一项外展计划，邀请附近学院的学生到我们的校园参加核磁共振研讨会和夏季研究机会。

This project is integrating nuclear magnetic resonance (NMR) theory and practice into the undergraduate chemistry curriculum. Initial experiments in organic chemistry laboratories focus on the interpretation of H1, C13, and NOE (Nuclear Overhauser Effect) spectra and how to elucidate structure using information obtained from chemical shifts, splitting patterns, coupling constants, and integration ratios. In subsequent coursework and laboratories, the nature of the FT-NMR experiment and instrument operating variables is being examined and problems involving reaction kinetics, magnetic moments of paramagnetic compounds, intramolecular rearrangements, 2-D methods, and other applications are being studied. Instruction of inexperienced undergraduates in the operation of the FT-NMR spectrometer is being augmented by video tapes that describe safety around magnets, sample preparation, instrument setup with step-by-step computer commands for the various experiments, data acquisition and processing, and the presentation of the spectra. The department additionally is conducting an outreach program whereby students at nearby colleges are invited to our campus for NMR workshops and summer research opportunities.