Organic and Organometallic Chemistry

这个无机、生物无机和有机金属化学项目的奖项为加州大学伯克利分校化学系Robert G. Bergman博士对有机金属反应机制的研究提供了持续的支持。努力将集中在三个项目上。第一个问题是在单个分子中，分别来自该系列的左右两侧的过渡金属之间的相互作用。第二个目标是生成由于金属中心存在不成对电子而具有高活性的有机金属配合物。在这些物种中，与金属形成了相对较强的共价键，因此通常不与金属结合的有机化合物可以与金属结合，然后表现出新的反应性。类似的18电子金属阴离子的化学性质也将包括在内。第三个项目是合成新的配体，赋予早期和晚期过渡金属配合物平面手性，以便研究以不对称诱导进行有机转化的金属中心反应的立体化学。开发新的金属二聚化催化剂，用于从二烯和多烯制备低聚物和具有特殊结构的聚合物。涉及有机分子和过渡金属配合物的化学反应是理解重要的催化和生物过程的基础。在这个程序中，一种或两种金属的存在施加空间限制或产生不寻常的电子驱动力的反应的细节将被研究。

This award in the Inorganic, Bioinorganic, and Organometallic Chemistry program provides continued support for studies of organometallic reaction mechanisms by Dr. Robert G. Bergman, Chemistry Department, University of California at Berkeley. Efforts will be focused on three projects. The first concerns interaction between transition metals from the left and right sides of the series, respectively, within a single molecule. A second goal is generation of organometallic complexes that are highly reactive due to the presence of an unpaired electron at the metal center. In such species, relatively strong covalent bonds are formed to the metal so that organic compounds that do not ordinarily associate with metals may bond and then exhibit new reactivity. Some chemistry of analogous 18-electron metal anions will also be included. The third project is the synthesis of new ligands that confer planar chirality on early and late transition metal complexes so that the stereochemistry of metal-centered reactions that carry out organic transformations with asymmetric induction may be investigated. New metal dimerization catalysts for preparing oligomers and polymers with unusual structures from dienes and polyenes will be developed. Chemical reactions involving organic molecules and transition metal complexes are fundamental to the understanding of important catalytic and biological processes. In this program, the details of reactions in which the presence of one or two metals imposes steric restrictions or develops unusual electronic driving forces will be investigated.