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Prototyping Biomolecular Computations

Prototyping Biomolecular Computations
生物分子计算原型
批准号:
9725021
负责人:
John Reif
金额:
$264.79万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-09-01 至 2002-04-30

项目摘要

项目成果

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中文摘要
翻译
生物分子计算(BMC)是一个非常有潜力的领域,因为在分子尺度上有大量的并行性。然而,现实的评估也必须考虑到这一领域的研究由于缺乏成熟度而具有相当大的风险。这是一个多小组的努力,包括美国的几个研究BMC的小组。这个项目的目标是组织这些团体的能量,以便利用可能超过个人努力的集体成就。该项目将强调基础设施的协同开发,以支持BMC,进一步开发和测试其基本能力。这些小组将调查BMC的关键方面。这些将包括:BMC的演示。关键的部分是:文字设计;用于存储和检索逻辑和数字信息的寄存器设计;基本运算的执行,如逻辑和算术运算,以及这些运算的顺序链接;数据的输入和结果的读出,并与硅基计算机接口;以及提高错误弹性的方法。新型三维结构的纳米结构。BMC的应用。这将包括:生物应用探索和演示棘手的NP搜索问题模拟问题的解决软件工具。用于仿真、设计和相关的数学模型。
英文摘要
Biomolecular Computation (BMC) is an area of great potential due to the massive parallelism available at the molecular scale. However, a realistic assessment must also take into account that research in this area possesses considerable risk, due to its lack of maturity. This is a multi-group effort encompassing several groups within the United States working on BMC. The goal of this project is to organize the energies of these groups so as to harness a collective accomplishments that may exceed the individual efforts. This project will emphasize collaborative development of the infrastructure in support of BMC, to further develop and test its basic capabilities. The groups will investigate key aspects of BMC. These will include: Demonstrations of BMC. The key subtakes are: word design; register design for storage and retrieval of logical and numeric information; execution of basic operations such as logical and arithmetric operations, and the sequential chaining of these operations; input of data and readout of results and interfacing with silicon-based computers; and methods to improve error resiliency. Nano-construction of New 3D Structures. Applications of BMC. This will include: biological applications exploration and demonstrations of intractable NP search problems solution of analog problems Software Tools. For simulation, design and associated mathematical models.
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