Integration of a GC-Ion Trap Mass Spectrometer into the Undergraduate Chemistry Curriculum

该项目的重点是改进上层化学实验室，这将是由GC离子阱质谱仪的收购促进。 在上师实验室，学生进行全面的调查超出了通常喜欢在许多“食谱”类型的实验室实验。每个项目持续两到四周，包括一些图书馆研究，样品制备和方法开发。GC-MS是这些实验室项目中的一个组成部分。 生物大分子的质谱分析已成为一种日益强大的生物分析技术。由于所需仪器的尺寸和成本，生物质谱法在大多数本科课程中缺席。在这个项目中，正在开发一个实验，使用GC-离子阱，将生物分析质谱的方法纳入课程。 本科生的研究项目，重点是气相色谱-质谱法的发展和气相热化学也正在进行中。 阿肯色州丰富的自然资源为环境相关的研究项目提供了许多机会。其中一个例子集中在将各种鸟巢散发的芳香与捕食者的感官联系起来。 我们还在有机实验室中使用GC-离子阱质谱仪来帮助鉴定有机合成的产物。

This project focuses on improvements in upper division chemistry laboratories that would be fostered by the acquisition of a GC-ion trap mass spectrometer. In the upper division laboratories, the students perform comprehensive investigations beyond what is normally fond in many 'cookbook" type laboratory experiments. Each project lasts for two to four weeks, and includes some library research, sample preparation, and method development. The GC-MS is an integral part in several of these laboratory projects. The mass spectrometry of large biomolecules has become an increasingly powerful bioanalytical technique. Due to the size and cost of the necessary instrumentation, biological mass spectrometry is absent from most undergraduate curricula. In this project an experiment is being developed using the GC-ion trap that integrates the methodology of bioanalytical mass spectrometry into the course curriculum. Undergraduate research projects focusing on GC-MS method development and gas-phase thermochemistry are also underway. Arkansas's abundant natural resources foster many opportunities for environmentally related research projects. One example focuses on relating the aromatics emanating from various bird nests to the senses of predators. We also are utilizing the GC-ion trap mass spectrometer in the organic laboratory to aid in the identification products from organic syntheses.