Upgrade of a 400-MHz NMR Spectrometer Vital for Chemistry Research and Education

在主要研究仪器（MRI）计划的支持下，科尔比学院化学系将升级400 MHz NMR光谱仪。该设备将使研究人员能够进行以下研究：a）天然产品的分离和鉴定; B）卡宾的合成和反应性; c）抗肿瘤剂的开发; d）核酸和肽的结构/功能关系;以及e）有机金属合成。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于从事前沿研究的化学家来说，使用最先进的NMR光谱分析技术是必不可少的。这些核磁共振研究的结果将在许多领域产生影响，包括药物开发和生物化学。

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Colby College will upgrade a 400 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) the isolation and identification of natural products; b) synthesis and reactivity of carbenes; c) antitumor agent development; d) nucleic acid and peptide structure/function relationships; and e) organometallic synthesis. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including drug development and biochemistry.