NER: Exploiting Nanoscopic Dendrimer Self-Organization in Catalysis

化学部授予俄亥俄州州立大学的这一奖项是纳米科学与工程计划中纳米探索性研究的一部分。 在该项目下，Jonathan Parquette将开发基于活性过渡金属（如钌和铜）的新型对映选择性催化剂，并将其纳入手性树枝状聚合物中。使用氨基吡啶二甲酰胺作为分支单元，手性非外消旋邻氨基苯甲酰胺作为末端单元，将制备多达三代的单树枝化基元。 树枝状聚合物与过渡金属将被评估为增强催化Diels-Alder和羟醛缩合反应。 此外，该研究计划还将为研究生和本科生提供材料化学方面的教育和培训机会。根据该奖项，将研究基于手性树枝状聚合物中活性过渡金属的新型对映选择性催化剂。树枝状聚合物，与多达三代，将被合成和他们的构象为基础的手性变化，在不同的溶剂中将使用圆二色性进行评估。 此外，不同的金属选择性地放置在树枝状聚合物的周边将被评估为增强的催化活性的手性材料的有机合成。 该研究计划将为研究生和本科生提供材料化学方面的教育和培训机会。

This award to Ohio State University by the Chemistry Division is part of the Nanoscale Exploratory Research in the Nanoscale Science and Engineering program. Under this project, Jonathan Parquette will develop novel enantioselective catalysts based on the active transition metals, such as ruthenium and copper, incorporated in chiral dendrimers. Monodendrons up to three generations will be prepared using aminopyridine dicarboxamide as the branching units, and chiral nonracemic anthranilamide as the terminal units. Dendrimers with transition metals will be evaluated for enhanced catalytic Diels-Alder and aldol condensation reactions. In addition, the research program will provide education and training opportunities in material chemistry to graduate and undergraduate students.Under the award, novel enantioselective catalysts based on the active transition metals in chiral dendrimers will be studied. Dendrimers, with up to three generations, will be synthesized and their conformationally based chiral changes in different solvents will be evaluated using circular dichroism. In addition, different metals selectively placed at the periphery of dendrimers will be evaluated for enhanced catalytic activities for the organic synthesis of chiral materials. The research program will provide education and training opportunities in materials chemistry to graduate and undergraduate students.