Conference: Post-Transcriptional Control of Gene Expression: Effectors of mRNA Decay to be held July 6-11, 2002 in Tucson, Arizona

美国实验生物学联合会将于2002年7月6日至11日在亚利桑那州图森市举行题为“基因表达的转录后控制：信使核糖核酸衰变的效应”的会议。这次会议的目的是为研究原核生物和真核生物中的信使核糖核酸衰变的工作者之间的思想交流提供机会。信使核糖核酸的衰变在决定基因表达水平方面起着主要作用。因此，了解信使核糖核酸降解的机制对于了解基因是如何被调控的非常重要。这次会议计划的主题包括：(1)会议开始时罗伊·帕克博士(亚利桑那大学)对信使核糖核酸衰变的主旨概述。(2)多组分细菌核酸酶。(3)多组分真核酸酶。(4)信使核糖核酸的转运和定位如何影响信使核糖核酸的衰变。(5)翻译的准确性如何影响信使核糖核酸的衰变，包括翻译的提前终止如何引起信使核糖核酸的衰变。(6)影响mRNA衰变的顺式作用信使核糖核酸序列及其相关的反式作用因子。(7)作为药物设计工具和靶点的RNA。

The Federation of American Societies of Experimental Biology (FASEB) conference entitled "Post-Transcriptional Control of Gene Expression: Effectors of mRNA Decay" will be held July 6-11, 2002 in Tucson, Arizona. The objective of this conference is to provide an opportunity for the cross-fertilization of ideas between workers studying mRNA decay in prokaryotes and eukaryotes. mRNA decay plays a major role in determining the level at which genes are expressed. Therefore, understanding the mechanisms of mRNA degradation becomes very important to understanding how genes are regulated. Among the topics planned for this conference are: (1) A keynote overview of mRNA decay at the start of the conference by Dr. Roy Parker (University of Arizona). (2) Multicomponent bacterial nucleases. (3) Multicomponent eukaroytic nucleases. (4) How mRNA transport and localization affect mRNA decay. (5) How translational accuracy affects mRNA decay, including how the premature termination of translation elicits mRNA decay. (6) Cis-acting mRNA sequences and their associated trans-acting factors that affect mRNA decay. (7) RNA as a tool and target for drug design.