Acquisition of a Sum Frequency Non-Linear Optical Spectroscopy System to Probe Interfaces of Nano, Bio and Environmental Materials

在主要研究仪器（MRI）计划的支持下，约翰霍普金斯大学化学和生物分子工程系将获得一个和频非线性光谱系统（SFG），以探测纳米，生物和环境材料的界面。该设备将用于探测a）微系统和传感器的有机薄膜界面; B）液体界面处的动态表面活性剂组件; c）微粒药物递送系统; d）脂质膜界面; e）细胞膜中钙粘蛋白的相互作用; f）疏水有机化学品与有机表面的相互作用;以及g）零价铁还原有机卤化物的反应中间体的鉴定。SFG系统将由博士后研究员、研究生和本科生使用。 约翰霍普金斯大学的SFG设备的存在也将影响教育课程，因为三名研究人员教授界面科学课程。该仪器将允许他们将激光光谱仪器和相关的非线性光学现象的例子纳入这些课程。

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemical and Biomolecular Engineering at Johns Hopkins University will acquire a sum frequency non-linear optical spectroscopy system (SFG) to probe interfaces of nano, bio and environmental materials. This equipment will be used to probe a) interfaces of organic thin films for microsystems and sensors; b) dynamic surfactant assemblies at liquid interfaces; c) microparticle drug delivery systems; d) lipid membrane interfaces; e) cadherin interactions in cell membranes; f) interactions of hydrophobic organic chemicals with organic surfaces; and g) identification of reaction intermediates in the reduction of organohalides by zero-valent iron. The SFG system will be used by post-doctoral fellows, graduate and undergraduate students. The presence of a SFG apparatus at Johns Hopkins University will also impact the education curriculum since three of the investigators teach courses in interfacial science. This instrument will allow them to incorporate examples of laser spectroscopic instrumentation and associated nonlinear optical phenomena into these courses.