Purchase of a Liquid Chromatograph-TOF Mass Spectrometer

凭借化学研究仪器和设施：部门多用户仪器采购（CRIF：MU）计划的这一奖项，位于滨江的加州大学化学系将获得液相色谱-飞行时间质谱（LCMS）系统。主要用户的项目包括：合成用于化学基因组学的组合库;发现未知/前所未有的化学反应;分析天然肽的外消旋作用;制备具有与分子长度成比例的偶极矩的共轭螺旋低聚物;开发新的卡宾钳形络合物作为加氢胺化等新型有机金属转化的催化剂;以及开发新的环状卡宾作为用于有机金属转化的上级配体，包括不对称配体。该仪器也将被加州大学河滨分校的其他研究人员和本科生实验室教学所使用。液相色谱-质谱检测是一种非常强大的技术，用于分离和分析复杂的混合物。 该仪器不仅将服务于化学，还将有助于推进植物细胞生物学和材料科学等领域的知识。

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multiuser Instrument Acquisition (CRIF:MU) Program, the Department of Chemistry at the University of California in Riverside will acquire a liquid chromatograph-time-of-flight mass spectrometry (LCMS) system. Projects of the major users include: synthesis of combinatorial libraries used in chemical genomics; discovery of unknown/unprecedented chemical reactions; analysis of natural peptides for racemization; preparation of conjugated helical oligomers having a dipole moment that scales with molecular length; development of new carbene pincer complexes as catalysts for novel organometallic transformations like hydroamination; and development of new cyclic carbenes as superior ligands, including asymmetric ligands, for organometallic transformations. The instrument will also be used by other researchers at UC-Riverside and in undergraduate lab instruction.Liquid chromatography with mass spectrometric detection is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will not only serve chemistry, it will contribute to advancing knowledge in fields such as plant cell biology and materials science.