Acquisition of a Cyber-Enabled Electron Paramagnetic Resonance Spectrometer

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。从化学研究仪器和设施多用户计划（CRIF：MU）获得该奖项，Vincent J. Catalano教授和同事Ana de Bettencourt-Dias，Jason Shearer和Robert S.位于里诺的内华达州大学的谢里丹将获得一个能够进行低温测量的网络电子顺磁共振（EPR）光谱仪。该光谱仪将推进研究金属蛋白生物化学的研究项目，研究弱生物分子相互作用，瞬态有机（双）自由基和卡宾，以及镧系元素MRI造影剂和发光材料的开发。通过使光谱仪具备网络功能，区域机构可以使用该光谱仪，EPR光谱仪可提供关于分子和分子电子结构的信息。它还可以用于获得有关自由基的寿命和身份的信息，自由基是通常对肿瘤生长和/或各种化学反应的起始至关重要的短寿命物质。这些研究将在许多领域产生影响，从化学到材料和生物化学。该仪器将成为教学和研究的一个组成部分。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), Professor Vincent J. Catalano and colleagues Ana de Bettencourt-Dias, Jason Shearer, and Robert S. Sheridan from University of Nevada at Reno will acquire a cyber-enabled electron paramagnetic resonance (EPR) spectrometer capable of low temperature measurements. This spectrometer will advance research projects studying biochemistry of metalloproteins, investigation of weak biomolecular interactions, transient organic (bi)radicals and carbenes, and development of lanthanide-based MRI contrast agents and luminescent materials. By cyber-enabling the spectrometer, it will be available to regional institutions.An EPR spectrometer yields information on the molecular and electronic structure of molecules. It may also be used to obtain information about the lifetimes and identities of free radicals, short-lived species that are often essential for the initiation of tumor growth and/or a variety of chemical reactions. These studies will have an impact in a number of areas, from chemistry to materials and biological chemistry. This instrument will be an integral part of teaching as well as research.