Acquisition of a Confocal Laser Scanning Microscope at the Bigelow Laboratory for Ocean Sciences

毕格罗海洋科学实验室获得了购买共焦激光扫描显微镜(CLSM)的赠款。在过去的几十年里，生物科学中的成像经历了复兴，一个重要的原因是共聚焦激光扫描显微镜(CLSM)的出现。激光共聚焦显微镜是活细胞图像分析的关键，包括研究细胞内结构，了解微生物生物膜的结构，以及为生态学研究同时进行多个微生物物种的原位鉴定。毕格罗实验室的研究人员研究了海洋中的各种过程，这些过程最终都是微生物的结果。因此，研究微观细胞和群落的成像工具对科学家的任务至关重要。广泛影响该仪器将帮助至少8名毕格罗科学家以及定期在该设施合作的各种外部合作者的研究。该设施拥有一个新的REU网站，培训许多博士后和学生实习生，每年举办一次高中培训课程(以及许多其他面向本科生的课程)，还举办一系列公开讲座。所有这些项目都强调了该设施的研究优势，这得益于新仪器的加入。推而广之，所有这些活动也将受益于拟议的增加。

Bigelow Laboratory for Ocean Sciences is awarded a grant to purchase a Confocal Laser Scanning Microscope (CLSM). Imaging in the biological sciences has undergone a renaissance in the last couple of decades, a significant reason for this has been the advent of confocal laser scanning microscopes (CLSM). The CLSM is the essential for live cell image analysis, including the investigation of intracellular structures, understanding the architecture of microbial biofilms, as well as the simultaneous identification, in situ, of multiple microbial species for ecological studies. Researchers at the Bigelow laboratory study a wide range of processes in the ocean that are ultimately the result of microorganisms. As a result, imaging tools for studying microscopic cells and communities are critical to the scientists mission.Broader ImpactsThe instrument will aid the research of at least 8 of the Bigelow scientists as well as a variety of external collaborators who regularly collaborate at the facility. The facility hosts a new REU site, trains numerous postdocs and student interns, holds an annual high school training course (and numerous other courses for undergraduates as well), and also hosts a public lecture series. All of these programs emphasize the facility's research strengths, which benefit from the addition of the new instrument. By extension, all of these activities will also benefit from the proposed addition.