Acquisition of a Console and Probes for an Upgrade of a 500 MHz NMR Spectrometer

来自肯特州立大学的Michael Tubergen教授及其同事Nicola Brasch、Songping Huang、Anatoly Khitrin和Edgar Kooijman获得了化学研究仪器和设施：多用户(CRIF：MU)计划颁发的这一奖项，他们将购买一个控制台和两个探测器(3通道自调探头和用于扩散研究的梯度探头)，以升级500 MHz核磁共振光谱仪。该奖项将加强各级的研究培训和教育，特别是在以下研究领域：(A)维生素B12衍生物与一氧化氮物种的反应；(B)量子放大、多量子技术和绝热交叉极化方法；(C)使用31P和1H单核和多核核磁共振研究蛋白质-脂质相互作用；(D)用于分子和细胞成像应用的普鲁士蓝类似物设计磁共振造影剂；(E)周期性介孔有机硅，和(F)液晶和有机半导体的19F分析。核磁共振光谱是化学家可用于阐明分子结构的最强大的工具之一。它被用来识别未知物质，跟踪化学反应的进展，表征分子内原子的特定排列，并研究固体和溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪对于开展前沿化学相关研究和培训学生掌握现代研究技术至关重要。这些核磁共振研究的结果将对有机、材料、电子学和生物有机化学研究产生影响。这些资源不仅将用于研究活动，还将用于本科生和研究生的研究培训，包括那些来自代表性不足群体的学生。

With this award from the Chemistry Research Instrumentation and Facilities: Multi-user (CRIF:MU) program, Professor Michael Tubergen and colleagues Nicola Brasch, Songping Huang, Anatoly Khitrin and Edgar Kooijman from Kent State University will acquire a console and two probes (3-channel self-tuning probe and a gradient probe for diffusion studies) to upgrade a 500 MHz NMR spectrometer. The award will enhance research training and education at all levels, especially in areas of study such as (a) reactions of vitamin B12 derivatives with nitric oxide species, (b) quantum amplification, multiple quantum techniques, and methods of adiabatic cross polarization, (c) protein-lipid interactions investigated using 31P and 1H single and multinuclear NMR, (d) designer MRI contrast agents from prussian blue analogues with high relaxivity for molecular and cellular imaging applications, (e) periodic mesoporous organosilicas, and (f) 19F analysis of liquid crystals and organic semiconductors.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to follow the progress of chemical reactions, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solids and in solution. Access to state-of-the-art NMR spectrometers is essential to carry out frontier chemistry related research and to train students in modern research techniques. The results from these NMR studies will have an impact on organic, materials, electronics and bioorganic chemistry research. The resources will be used not only for research activities but also for research training of undergraduate and graduate students including those from underrepresented groups.