International: Collaborative Advancement in Analytical and Theoretical Metapopulation Statistical Genetics

该项目支持道格拉斯泰勒博士和他的学生彼得·菲尔兹先生在弗吉尼亚大学生物系和奥斯卡·加焦蒂博士在生物学系的合作。法国格勒诺布尔大学的生态阿尔卑斯山。该提案将资助菲尔兹在2011年秋季和2012年夏季对格勒诺布尔大学的两次长期访问。该合作将开发分析和计算方法，以分析来自自然种群的遗传数据。拟议的研究利用Gaggiotti？的专业知识，在人口遗传分析和软件设计和无与伦比的24年以上的集合种群数据集的被子植物宽叶蝇子草。这项合作是一个令人兴奋的机会，可以通过长期的集合种群数据集来完善统计工具和地面实况群体遗传学方法。拟议的研究将允许更好地了解空间分布的种群或集合种群的遗传学。此外，拟议的研究将解析随机和选择力在形成遗传多样性模式中的相对作用。了解集合种群的进化过程对于保护生物学、入侵生物学以及理解生境破碎化的潜在响应具有重要的实际意义和应用价值。就可交付成果而言，所产生的软件将免费提供给研究人员，在GNU通用公共许可证下出版，由自由软件基金会分发（http：//www.gnu.org/licenses/）。

This project supports a collaboration between Dr. Douglas Taylor and his student, Mr. Peter Fields, in the Department of Biology at the University of Virginia, and Dr. Oscar Gaggiotti in the Laboratoire d?Ecologie Alpine at the University of Grenoble in France. This proposal will fund two long-term visits for Fields to the University of Grenoble in the Fall of 2011 and Summer of 2012. The collaboration will develop analytical and computational methods to analyze genetic data from natural populations. The proposed research leverages Gaggiotti?s expertise in population genetic analysis and software design and an unparalleled 24+ year metapopulation dataset of the angiosperm Silene latifolia. This collaboration is an exciting opportunity to refine statistical tools and ground truth population genetics methods with a long-term metapopulation dataset. The proposed research will allow for better understanding of the genetics of spatially distributed populations, or metapopulations. Additionally, the proposed research will parse out the relative roles of random and selective forces in shaping patterns of genetic diversity. Understanding evolutionary processes in metapopulations is of practical and applied importance for conservation biology, invasion biology, and for understanding potential responses to habitat fragmentation. In terms of deliverables, resulting software will be made freely available to researchers, being published under the GNU General Public License and distributed by the Free Software Foundation (http://www.gnu.org/licenses/).