Supporting young scientists to attend the Gordon Research Conference Centromere Biology:The Genomics and Epigenomics of Centromere Function and Dysfunction; Waltham, MA-7/27-8/1/14

着丝粒是细胞分裂期间驱动染色体运动的染色体位点。着丝粒的正常功能需要一个复杂的级联事件，涉及数百种不同蛋白质的组装，然而，这种级联过程的精确机制仍然是未知的。 在每个细胞周期中，蛋白质未能在着丝粒处组装，最终导致染色体错误分离和随后细胞周期中的细胞分裂缺陷，从而导致细胞分裂缺陷。在过去的十年中，一些显著的发现已经导致了在参与着丝粒维持的蛋白质组装中的一些关键参与者的鉴定。 2014年会议？戈登研究会议：着丝粒生物学？是第一个汇集了科学家谁拥有共同的兴趣，在阐明组织，组装和动力学的着丝粒，细胞结构是至关重要的基本细胞过程和进化的一个物种。着丝粒生物学的主题通常在其他染色体和着丝粒会议上代表不足，或者在许多不同的会议上广泛分散和稀释。通过突出不同的方法和新发现，本次会议旨在推动着丝粒生物学领域的进展，从理解蛋白质组装和生化途径到定义遗传模式。本次会议将促进具有共同专业兴趣的科学家之间的讨论，并从各自领域的先进方面交流思想，使科学合作能够朝着新的方向发展。本次会议是一个独特的机会，鼓励合作和讨论的新发现，因为未发表的数据是主要的重点提出的材料。场地和程序的组织，以促进欢迎，包容的气氛，为年轻的科学家和学生介绍他们的工作，并通过海报会议和非正式讨论交换意见。相对较少的与会者（约100-150人）将为处于科学生涯关键阶段的年轻参与者提供网络机会，指导和新研究的观点。每次会议将包括一到两个会谈，根据会议的长度，从提交的摘要中选择。这些选定的会谈将针对后期突破性的发现以及早期的职业科学家。这一请求的目标是支持特殊的早期职业科学家在研究界以及实习生，如博士后和研究生在这一领域工作的不同背景参加着丝粒生物学戈登研究会议2014。NSF的资助将为与会者提供注册费和/或差旅费支持，并优先考虑博士后和研究生参加会议。

The centromere is the chromosomal locus that drives chromosome movement during cell division. The proper functioning of centromeres requires a complex cascade of events involving assembly of hundreds of different proteins, however, the precise mechanism by which this cascade proceeds is still largely unknown. Failure to assemble the proteins at centromeres during each cell cycle ultimately leads to chromosome mis-segregation and cell division defects in subsequent cell cycles, leading to cell division defects. Remarkable discoveries in the past decade have led to the identification of a few key players in the protein assembly involved in centromere maintenance. The 2014 meeting ?Gordon Research Conference: Centromere Biology? is the first to bring together scientists who share a common interest in elucidating the organization, assembly and dynamics of the centromere, the cellular structure that is critical to the basic cellular processes and evolution of a species. The topic of centromere biology is typically under-represented at other chromosome and centromere meetings, or alternatively, is widely dispersed and diluted across many different conferences. By highlighting diverse approaches and new discoveries, this conference aims to spur progress in the field of centromere biology across a myriad of topics, from understanding protein assembly and biochemical pathways to defining patterns of inheritance. This conference will promote discussion between scientists with common professional interests and the exchange of ideas from advanced aspects of their field, enabling scientific collaborations to evolve in new directions. This conference represents a unique opportunity to encourage collaboration and discussion of new discoveries, since unpublished data is the main focus of presented material.The venue and the program are organized to promote a welcoming, inclusive atmosphere for junior scientists and students to present their work and exchange ideas through poster sessions and informal discussions. The relatively small number of attendees (~100-150) will provide networking opportunities, mentoring, and perspectives on new research for younger participants at a critical stage in their scientific careers. Each session will include one to two talks, depending on the session length, chosen from the submitted abstracts. These selected talks will be targeted towards late breaking discoveries as well as early career scientists. The goal of this request is to support exceptional early career scientists in the research community as well as trainees such as postdocs and graduate students working in this field with diverse backgrounds to attend the Centromere Biology Gordon Research Conference 2014. The funding from NSF will provide support for registration fee and/or travel support for participants, with preference given to post docs and graduate students to attend the meeting.