Gene therapy to enhance auditory prosthesis performance for cochlear implants

人工耳蜗是最有效的神经义肢，能使聋人恢复听力。这项研究的目的是开发一种新型的植入物，可以将治疗基因传递到耳蜗内壁的细胞中。基因治疗DNA构建将被开发，将提高神经存活和生长，提高人工耳蜗的性能。这项研究将为了解如何将基因转移到耳蜗组织以及开发有效的神经修复基因磁带提供进展。这项工作将推动仿生学领域的发展，这是澳大利亚正在建立国际领先地位的领域。

The cochlear implant is the most effective neural prosthesis, restoring hearing to the deaf. The research aims to develop a new type of implant compatible with delivery of therapeutic genes to the cells lining the cochlea. Gene therapy DNA constructs will be developed that will enhance neural survival and growth, improving cochlear implant performance. The research will provide advances in understanding how to transfer genes into cochlear tissue, as well as development of gene cassettes for effective neural repair. The work will advance the field of bionics, an area where Australia is establishing international preeminence.