Amino acids as nutrients - the molecular basis of amino acid absorption in kidney and intestine

营养是幸福和健康的关键因素。这突出表现为II型糖尿病发病率的增加和所有西方饮食社会面临的肥胖问题。大多数营养学研究都集中在脂肪和碳水化合物上，因为它们直接参与肥胖和糖尿病。然而，蛋白质和由此产生的肽和氨基酸构成了我们营养的10-15%。在推荐富含蛋白质的饮食来对抗肥胖和糖尿病的时候，重要的是要了解蛋白质吸收和代谢的基础。本研究旨在探讨氨基酸在肾脏和肠道中的吸收机制和介质。

Nutrition is a critical factor for well being and health. This is highlighted by the increase in frequency of type II diabetes and the obesity problem that all societies with a western diet face. Most studies in nutrition focus on fat and carbohydrates because of their direct involvement in obesity and diabetes. Proteins and the resulting peptides and amino acids, however, form 10-15% of our nutrition. At a time where protein-rich diets are recommended to fight obesity and diabetes, it is important to understand the basis of protein absorption and metabolism. This project investigates the mechanism and mediators of amino acid absorption in kidney and intestine.