MRI: Acquisition of a Flow Cytometer/Sorter (FCMS) at Lamar University

获得一台流式细胞仪/细胞分选仪将使Lamar大学的一个多学科研究人员和学生小组能够进行包括定量单细胞生物学分析和分选在内的分析。该仪器将促进与阿尔茨海默病治疗筛选和鉴定、高通量药物筛选、独特癌症类型和标志物鉴定以及环境毒素分析相关的研究。这些设备的可用性将增加拉马尔大学内部以及与其他组织的跨学科和跨部门合作研究机会，并将丰富研究生和本科生的培训。微生物学、生物化学、化学工程、土木与环境工程等专业的研究生和本科生都可以使用该工具，从而加强本科生和研究生的课程内容。流式细胞术/细胞分选是一种以高通量方式对每个细胞进行高水平定性和定量分析的技术。收购流式细胞仪/细胞分选仪将产生进行高种群计数，定量单细胞生物学分析和分选的能力。因此，该仪器的可用性将促进与药物发现、生物燃料、环境影响、衰老和癌症表征相关的研究。这样的工作将显著改善与体外研究相关的研究，包括高通量药物筛选、独特癌症类型和标记物的鉴定以及环境毒素的测定。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The acquisition of a flow cytometer/cell sorter will enable a multi-disciplinary group of researchers and students at Lamar University to perform analyses that involve quantitative single cell biological analysis and sorting. The instrument will facilitate research associated with Alzheimer's disease therapeutic screening and identification, high throughput drug screening, identification of unique cancer types and markers, and analysis of environmental toxins. The availability of this equipment will increase interdisciplinary and interdepartmental collaborative research opportunities within Lamar University as well as with other organizations, and it will enrich the training of graduate and undergraduate students. Graduate and undergraduate students in microbiology, biochemistry, chemical engineering, and civil and environmental engineering classes will have access to this instrument, thereby strengthening curriculum content at the undergraduate and graduate levels.Flow cytometry/cell sorting is a technique for doing high level qualitative and quantitative analysis on a per cell basis for large cell populations in a high-throughput manner. The acquisition of a flow cytometer/cell sorter will generate the capability to perform high population count, quantitative single cell biological analysis and sorting. The availability of this instrument, therefore, will facilitate research related to drug discovery, biofuels, environmental impact, aging, and cancer characterization. Such work will lead to significantly improved research related to in vitro studies, including high throughput drug screening, the identification of unique cancer types and markers, and the determination of environmental toxins.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.