MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance (NMR) Spectrometer at Miami University

该奖项由主要研究仪器和化学仪器项目支持。俄亥俄州迈阿密大学的Christopher Hartley教授及其同事Michael Crowder、Meredith Erb、Dominik Konkolewicz和wei Liu正在获取一台400 MHz核磁共振(核磁共振)光谱仪，该光谱仪配备了用于监控动力学的流动监测附件和自动取样器。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及促进对生物相关物种的研究。总的来说，核磁共振波谱是化学家用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。核磁共振研究提高了对合成有机/无机化学、材料化学和生物化学的理解。该仪器是教学和研究不可分割的一部分。这种可广泛使用的仪器加强了地区性的核磁共振分析基础设施，并有助于促进许多经常使用本科生和研究生研究人员和博士后的科学事业。该光谱仪丰富了NSF资助的几个科学、技术、工程和数学(STEM)项目中未被充分代表的本科生的教育和培训经验，以及该机构数百名化学和生物化学实验班的本科生。该奖项旨在加强各级的研究和教育。该光谱仪特别适用于研究邻苯二胺和非平衡体系，以及监测氟化反应。对聚合反应、小分子反应和金属β-内酰胺酶的动力学研究也是必不可少的。该光谱仪帮助研究人员探索高自旋钴(II)的配位化合物，以及研究对映体选择性催化。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Instrumentation Programs. Professor Christopher Hartley from Miami University in Ohio and colleagues Michael Crowder, Meredith Erb, Dominik Konkolewicz and Wei Liu are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with flow monitoring accessory to monitor kinetics and an automatic sampler. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as facilitating studies of biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research. This broadly accessible instrumentation strengthens the regional NMR analytical infrastructure and help advance the scientific careers of many regular users of undergraduate and graduate researchers and postdocs. The spectrometer enriches the education and training experience of underrepresented undergraduate students in several NSF supported science, technology, engineering and mathematics (STEM) programs and several hundred undergraduate students in chemistry and biochemistry laboratory classes at this institution.The award is aimed at enhancing research and education at all levels. The spectrometer is especially useful for studying o-phenylene foldamers and non-equilibrium systems and for monitoring flurorination reactions. It is also essential or studying kinetics of polymerization and small-molecule reactions and metallo-beta-lactamase enzymes. The spectrometer aids researchers exploring coordination compounds of high-spin cobalt(II) and those studying enantioselective catalysis. It is also in exploration of heterogeneous electrocatalysis of carbon dioxide and methane.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.