MRI: Acquisition of a Single-Crystal X-Ray Diffractometer

该奖项由主要研究仪器项目和化学研究仪器项目支持。加州大学圣克鲁斯分校正在购买一台单晶X射线衍射仪，以支持斯科特·奥利弗教授和他的同事：普拉迪普·马沙拉克、斯科特·洛基、约翰·麦克米兰和蒂莫西·约翰斯通。通常，X射线衍射仪可以准确和精确地测量分子的完整三维结构，包括键距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。这里描述的研究影响到许多领域，包括有机化学和无机化学、材料化学和生物化学。该仪器是该学院以及其他系化学和生物化学专业本科生教学、科研和培训不可或缺的一部分。该仪器带来的科学有可能通过开发解决环境污染和能源生产的新材料以及改进商品和工业化学品合成的新催化剂来影响这个拉美裔服务机构(HSI)的社会。此外，该仪器还为少数族裔进入研究职业计划和访问等项目的学生提供了直接的研究经验，这是一个为希望从事研究科学事业的社区大学生提供学术桥梁的项目。该大学允许附近的两年制社区学院和四年制高等教育机构免费使用这种仪器。授予X射线衍射仪的目的是加强各级的研究和教育。通过开发解决环境污染和能源生产的新材料，以及改进商品和工业化学品合成的新催化剂，该仪器带来的科学提供了相关的社会效益。该仪器用于研究主族生物无机化学和可能在药物输送中使用的化合物。此外，该仪器的收购有利于探索海洋天然产品，有可能发现可能的治疗靶点和治疗方法。衍射仪还用于表征高压和变温矿物物理。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. The University of California Santa Cruz is acquiring a single crystal X-ray diffractometer to support Professor Scott Oliver and colleagues: Pradip Mascharak, Scott Lokey, John MacMillan and Timothy Johnstone. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighbors. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this institution as well other departments. The science enabled by this instrument has the potential to impact society at this Hispanic-Serving Institution (HSI) through the development of new materials to address environmental pollution and energy production, and new catalysts to improve the synthesis of commodity and industrial chemicals. In addition, the instrumentation provides direct research experience for students in programs like the Minority Access to Research Careers Program and ACCESS, an academic bridge program for community college students who want to pursue careers in research science. The university allows nearby 2-year community colleges and 4-year post-secondary institutions that are also HSIs to have access to this instrumentation free of charge.The award of the X-ray diffractometer is aimed at enhancing research and education at all levels. The science enabled by this instrument provides relevant societal benefits through the development of new materials to address environmental pollution and energy production, and new catalysts to improve the synthesis of commodity and industrial chemicals. The instrumentation is used for studying main-group bioinorganic chemistry and compounds that may have the potential for use in the delivery of medicines. In addition, the instrument acquisition benefits exploration of marine natural products with the potential to discover possible therapeutic targets and therapeutics. The diffractometer is also used to characterize high-pressure and variable-temperature mineral physics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.