Conference: FASEB 2024 Conference on Genetic Recombination and Genome Rearrangements

该奖项是为了支持将于2024年7月14日至19日在亚利桑那州图森举行的基因重组和基因组重排会议。这是一个成熟的会议，自1985年以来每两年举行一次。会议将包括8次全体会议，每次会议将有5至8次20分钟的发言。大约三分之二的演讲者是受邀的，其余的将从投稿的摘要中选出，重点是早期的职业科学家。此外，大约70名提供海报的初级参与者也将进行简短的海报入门讲座，介绍他们自己和他们的海报主题。这次会议将有200多名与会者，他们代表了从实习生到成熟的PI的所有职业阶段。组委会将特别努力为不同的青年科学家提供全体演讲机会。值得注意的是，所有NSF的资金将用于支持受训者和年轻研究者的参与，重点是那些历史上代表性不足的群体以及有经济需要的群体。会议将集中讨论重组及其对基因组重排、突变、DNA修复和染色体功能的影响。这些主题将从多个机制角度进行探讨，包括重组中涉及的蛋白质的结构和生物物理分析，以及重组对基因组结构的影响的基因组分析。会议将强调利用分子遗传学、生物化学和结构生物学等前沿方法推动的突破，这些方法应用于DNA损伤反应、染色质重塑以及复制、转录和重组的一般过程。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is for support of the conference Genetic Recombination and Genome Rearrangements, to be held July 14-19 2024 in Tucson, Arizona. This is a well-established conference that has occurred biennially since 1985. The meeting will include 8 plenary sessions, each of which will have 5 to 8 20 minute presentations. Approximately two-thirds of the speakers are by invitation, and the remainder will be selected from contributed abstracts, with an emphasis on early career scientists. In addition, approximately 70 junior participants giving posters will also be giving short Poster Primer talks, introducing themselves and their poster topics. This meeting will have over 200 participants representing all career stages, from trainees to established PI’s. The organizing committee will make a special effort to provide plenary speaking opportunities to diverse junior scientists as well. Notably, all NSF funds will be used to support participation by trainees and young investigators, with an emphasis on those from historically underrepresented groups as well as those with financial need.The conference will focus on the topic of recombination and its implications for genome rearrangement, mutation, DNA repair and chromosome function. These topics will be explored from multiple, mechanistic perspectives, including structural and biophysical analyses of the proteins involved in recombination, and genomic analyses of the consequences of recombination for genome structure. The meeting will emphasize breakthroughs spurred by cutting-edge approaches using molecular genetics, biochemistry and structural biology, as applied to DNA damage responses, chromatin remodeling, and the general processes of replication, transcription and recombination.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.