Genomic analysis-based neuropharmacological study on basal ganglia-thalamocortical circuits for new drug discovery in schizophrenia
Genomic analysis-based neuropharmacological study on basal ganglia-thalamocortical circuits for new drug discovery in schizophrenia
批准号:
20H03428
负责人:
Yamada Kiyofumi
金额:
$11.32万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2020
资助国家:
日本
项目状态:
已结题
起止时间:
2020-04-01 至 2023-03-31
中文摘要
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英文摘要
期刊论文(20)
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DOI:
10.1016/j.bbr.2021.113569
发表时间:
2021-09
期刊:
Behavioural Brain Research
影响因子:
2.7
作者:
[Jingzhu Liao;Geyao Dong;Bolati Wulaer;Masahito Sawahata;H. Mizoguchi;D. Mori;N. Ozaki;T. Nabeshima;T. Nagai;Kiyofumi Yamada]
通讯作者:
Jingzhu Liao;Geyao Dong;Bolati Wulaer;Masahito Sawahata;H. Mizoguchi;D. Mori;N. Ozaki;T. Nabeshima;T. Nagai;Kiyofumi Yamada
Comprehensive Phosphoprotemic Analysis in Reelin Mutant Mice Revealed a Crucial Rolr of Twinfilin-1 in Spine Development.
Reelin 突变小鼠的全面磷酸化蛋白质分析揭示了 Twinfilin-1 在脊柱发育中的关键作用。
DOI:
--
发表时间:
2021
期刊:
影响因子:
--
作者:
[Norimichi Ito, Takaaki Matsui, Ayato sato, Kazuhiro Hada, Yumi Tsuneura, Taku Nagai, Toshitaka Nabeshima, Kiyofumi Yamada]
通讯作者:
Kiyofumi Yamada
Microinjection of Reelin into the mPFC prevents MK-801-induced recognition memory impairment in mice
将 Reelin 显微注射到 mPFC 中可预防 MK-801 诱导的小鼠识别记忆障碍
DOI:
10.1016/j.phrs.2021.105832
发表时间:
2021
期刊:
Pharmacological Research
影响因子:
9.3
作者:
[Sawahata Masahito, Asano Hiroki, Nagai Taku, Ito Norimichi, Kohno Takao, Nabeshima Toshitaka, Hattori Mitsuharu, Yamada Kiyofumi]
通讯作者:
Yamada Kiyofumi
Arhgap10遺伝子変異マウスの神経活動の解析にむけたin vivoカルシウムイメージング法の確立
Arhgap10基因突变小鼠体内钙成像分析神经活动方法的建立
DOI:
--
发表时间:
2022
期刊:
影响因子:
--
作者:
[田中里奈子, 羽田和弘, 溝口博之, 澤幡雅仁, 永井拓, 森大輔, 鍋島俊隆, 貝淵弘三, 尾崎紀夫, 山田清文]
通讯作者:
山田清文
Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia.
法舒地尔(一种 Rho 激酶抑制剂)在精神分裂症药理动物模型中的抗精神病样作用。
DOI:
10.1016/j.ejphar.2022.175207
发表时间:
2022
期刊:
European Journal of Pharmacology
影响因子:
5
作者:
[Takase S, Liao J, Liu Y, Tanaka R, Miyagawa Y, Sawahata M, Sobue A, Mizoguchi H, Nagai T, Kaibuchi K, Ozaki N, Yamada K.]
通讯作者:
Yamada K.
共 15 条
Significance of neovascularization of carotid plaque as a new preventive factor for ischemic stroke
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批准号:18K15568
-
项目类别:Grant-in-Aid for Early-Career Scientists
-
资助金额:$2.33万
-
财政年份:2018
-
负责人:Yamada Kiyofumi
-
依托单位:
Development a translatable visual discrimination test in rodents to apply for drug discovery and development
-
批准号:17H04031
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.48万
-
财政年份:2017
-
负责人:Yamada Kiyofumi
-
依托单位:
Development of a new transgenic mouse model as a platform for the imaging-based drug discovery and development
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批准号:16K15201
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2016
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负责人:Yamada Kiyofumi
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依托单位:
Study on the neuronal circuit and molecular mechanis underlying decision-making and its application for drug development
-
批准号:26293053
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.32万
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财政年份:2014
-
负责人:Yamada Kiyofumi
-
依托单位:
Real-time imaging of the mechanism underlying neuroinflammation-induced neuropsychiatric disorders
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批准号:26670121
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2014
-
负责人:Yamada Kiyofumi
-
依托单位:
海外基金