Research of Microactuators Applied to Intravascular Microvehicles

该项目旨在开发用于血管内使用的微机械及其设计和制造技术。该项目是国内首次尝试生产医用微机械，也是国内第一个建立医学工程研究的微机械中心。该项目于1988年9月开始，并建立了一个微机械制造系统，其中硅工艺和光刻技术成为适用。在该系统中，可以使用2英寸直径的硅晶片，并且已经开发了肌节状集成微致动器。为了在三维空间中加工和装配微小零件，介绍了一种微操作系统和一种三轴加工系统，并加工出许多微小零件。利用该系统研制了毫米级微型人工心脏瓣膜。为了开发血管内机器，我们应用了另一个生物医学项目开发的激光血管成形系统。设计并组装了带系绳的微型血管内车辆。在这种发展趋势下，我们提出了一种新的微执行器设计原理，并对其理论背景进行了研究。

The project was aimed at developing micromachines for intravascular use itself and their designing and fabrication technologies. The project is the first trial for producing the micromachine in medicine and also establishing the first micromachine center in the medical engineering research. The project was started on September, 1988, and built a micromachine fabrication system where silicon process and photolithography technology became applicable. In the system, a silicon wafer of 2 inch diameter can be used, and sarcomere like integrated microactuators has been developed. For machining and assembling microparts in the three dimensional space, a micromanipulation system and a three axial machining system were intoduced and many microparts were produced. A micro artificial heart valve in millimeter size has been developed with the system. For developing intravascular machines, we have applied laser angioplasty systems, which were developed another biomedical project The micro-intravascular vehicles with tethers has been designed and been assembled. Under the pathway of these development, we found a new microactualer designing principle, and its theroretical background has been studied.