Mechanisms of the development of neuronal cell community in the central nervous system

我们已经集中在新皮层神经元的迁移过程中，并确定了许多基因，优先表达的细胞下的边缘区。此外，我们已经确定了几个基因在层形成和迁移细胞动力学的功能。我们还发现了顶叶前体细胞和基底叶前体细胞的直接后代在发育中的新皮层中迁移行为的差异。前者在心室区上方停留近1天，我们称之为多极细胞聚集区（MAZ）。

We have focused on the migration process of neocortical neurons and identified many genes that are preferentially expressed in cells just beneath the marginal zone. In addition, we have identified functions of several genes in layer formation and migrating cell dynamics. We have also found the differences of migratory behavior between direct progeny of apical progenitors and basal progenitors in the developing neocortex. The former stay above the ventricular zone for almost 1 day, where we named the multipolar cell accumulation zone (MAZ).