Development of a New Type of Electronic Nose System Running on Artificial-intelligence Softwear

我们以前曾报道过，用电子鼻在高音模式下确定的分数提供了客观的口臭相关测量，但通过多元线性回归方法获得的分数仅显示相对值而不是绝对值。本研究的目的是临床评估呼吸空气中包括挥发性硫化物（VSC）在内的9种挥发性有机化合物（VOCs），并使用电子鼻（EN）系统评估以绝对值表示的临床口腔恶臭强度。18名健康成人和23恶臭患者进行了评估，使用感官测试的结果，浓度的VSCs使用气相色谱法和代表恶臭强度的每个系列的挥发性有机化合物与EN的分数。硫化氢和一系列含硫化合物对感官评分的贡献分别为21%和25%。此外，胺类化合物和芳香族化合物对感官评分的影响分别为18%和8%。EN法VOS强度总分与感官评分的相关系数为0.76。这些结果表明，气味评估的各种挥发性有机物与EN可以给出准确的评价口腔恶臭和口腔恶臭强度表示的绝对值，使用电子鼻可能是有用的，口腔恶臭的临床评估。

We have previously reported that the score as determined under top-note mode with an electronic nose provides objective halitosis-related measurements, but those obtained by the multiple linear regression method show only relative and not absolute values. The objective of this investigation was to assess clinically nine series of volatile organic compounds(VOCs) including volatile sulfur compounds(VSCs) in breath air and to assess clinically oral malodor intensity expressed as an absolute value using electronic nose(EN) system. Eighteen healthy adults and 23 malodor patients were assessed using results of an organoleptic test, concentration of VSCs using gas chromatography and a score representing malodor strength of each series of VOCs with an EN. Contribution of hydrogen sulfide and series of sulfur compounds to organoleptic score revealed 21 and 25%, respectively. In addition, series of amine and aromatic compounds also affected 18 and 8%, respectively for organoleptic score. The correlation coefficient between total intensity scores of VOSs using EN and organoleptic scores was 0.76. These results suggest that odor assessment of various VOSs with EN may give accurate evaluation of oral malodor and oral malodor intensity expressed an absolute value using electronic nose may be useful for evaluating clinically oral malodor.