Search for the biologically active substances from the marine invertebrates in the Caribbean

海洋环境已被证明是极其有效的化合物的丰富来源，这些化合物在抗肿瘤、抗炎、镇痛、免疫调节、过敏和抗病毒检测中显示出显著的活性。特别是，加勒比海的海洋无脊椎动物提供了各种各样的化合物。其中，胞外抗菌素743是一种已知的抗肿瘤化合物。在这个项目中，我们收集了加勒比海的海洋无脊椎动物，并准备了用于药物发现筛选的样本。

The marine environment has proven to be a rich source of extremely potent compounds that have demonstrated significant activities in antitumor, antiinflammatory, analgesia, immunomodulation, allergy, and antiviral assays. Especially, the marine invertebrates in the Caribbean afforded the variety of compounds. Among them ecteinascidin 743 was known to be an antitumor compound. In this project we collected marine invertebrates in the Caribbean and prepared samples for screening of drug discovery.