Diversity of mycotic zoonoses and the elucidation of the clinical symptom

由生境条件真菌引起的真菌性人畜共患病是一个严重的公共卫生问题。为此，笔者对真菌性人畜共患病的真菌学、生态学、流行病学和临床病理学进行了研究。由病原体引起的真菌性人畜共患病的多样性正在极大地发展。特别是本工作的调查是在前人文献报道的基础上进行的。结果表明：(1)民居真菌分布：真菌主要分布在浴室、卫生间、厨房等潮湿环境周围的毛霉属（Rhizopus）、枯霉属（Absidia）、毛霉属（Mucor）、马氏菌属（Martierella）等；emer冰岛远离灰尘，榻榻米，并且是比较干燥的地区。念珠菌分离于人、动物表面或粘膜，也分离于更衣室和浴室。(2)真菌人畜共患病的多样性：在宠物诊所，作者对疾病标本进行了采样，并从病原体中分离出来。我国真菌病以皮肤真菌病为主，其次为曲霉病、真菌病、镰刀菌病、念珠菌病和隐球菌病。机会致病菌在城市间建筑物等居住环境中呈逐渐增加趋势，而在农村地区呈逐渐增加趋势。(3)病原菌的生物学和流行病学研究：病原菌具有胞外代谢产物生产能力等生物活性，其中包括蛋白水解酶。其中，细粒美青霉、烟曲霉、a.t areus和Scopulariopsis具有较高的蛋白水解活性。此外，合菌、塞多孢子菌、艾美塞菌和烟曲霉具有溶血活性。这次真菌人畜共患病的调查和流行病学监测，显然表明了公共卫生和居住环境方面的现有信息。

Mycotic zoonoses caused by opportunistic fungi in dwelling ace seriously important problem as well as public health. Therefore, the authors were investigated on the mycology, ecology, epidemiology and clinical pathology of mycotic zoonoses. The diversity of mycotic zoonoses caused by pathogens was extremely progressing. Especially the investigation in this work was carried out the previous results which reported in other papers. The results were showed as followings ;(1)Fungal distribution in dwellings : The fungi were mainly distributed in Mucorales as Rhizopus, Absidia, Mucor, Martierella, dematious hyphomycetes as Exophiala, Aureobasidium around wet environments as like bath room, lavatory kitchen. Emericelh was isolated from dusts, Tatami and close which was somewhat dry area. Candida was isolated from human and animal surface or mucous membrane, and also isolated from clothes-changing room and bath room.(2)The diversity of mycotic zoonoses : With the pet clinics, the authors were sampling with the specimens from the disorderand isolated from the pathogens. The main mycotic diseases were dermatophytoses in this country and the following diseases were Aspergillosis, Zygomycoses, Fusariosis, Candidiosis and Cryptococcosis. The opportunistic pathogens were gradually increasing in dwelling environments like as the interurban buildings rather than rural areas.(3)The biological and epidemiological studies in the pathogens : The pathogens had a biological activities like the producibility of extracellular metabolites in which included proteolytic enzyme. The high proteolytic activities were showed by Emericella nidulans, Aspergillus fumigatus, A.terreus and Scopulariopsis. Furthermore, the zygomycetes, Scedosporium, Emericella and Aspergillus fumigatus showed the hemolytic activities.This investigation on the mycotic zoonoses and epidemiological surveillance apparently suggested the available information in public health and also dwelling environments.