Role of No-cGMP system on blockade of descending inhibitory system by anesthetics in spinal code

它强烈地呼吁术后立即疼痛，特别是在许多情况下不到8小时。提示cGMP转运系统在麻醉或止痛中发挥了重要作用。有一种可能性是吸入麻醉剂在低浓度时会引起意识过敏。这种意识--麻醉药物在脊柱内的下行控制拦截被认为是敏感产生及其延续的机制之一。一氧化氮合酶抑制剂和7-硝基吲唑(7-NI)是前年研究的HAROTAN。MAC和翻正反射ED50结果表明，它影响(RR)。在肉眼手术中，周围神经上看不见的损伤是无法避免的。产生意识超敏不仅与吸入麻醉剂有关，而且与周围神经的障碍有关。夏普PA…由周围神经障碍引起的更多的过敏症也可以认为脊柱中尖锐的疼痛控制机制没有有效地作为产生的原因之一。根据吸入麻醉剂产生的刺激性疼痛--根据对周围神经的损伤敏感的刺激性疼痛--为了研究敏感的常见机制，发展了一种新的刺激性疼痛敏感模型。传统的Chung等人的手术方法是从背侧入路入路，手术过程中损伤细神经的可能性较大，造成对侧剧烈疼痛过敏。即使手术一侧的意识超敏反应发生在从我们腹侧入路的半个物体中，它也是很小的，事实证明，这一次为了澄清脊柱的下行控制拦截是有利的。我们在详细检查前一年资料的结果--传统的钟氏等人方法--和控制--意识--的神经损伤手术，在敏感等级上出现了很大的差异。由于这种现象不是从过敏侧进入的，所以这次手术不一定是钟的模式和相同的，再次从后面重做手术的必要性出来了，本财年重做了。结果--控制--意识--差异仍然出现在敏感年级。有人认为，根本性的差异可能是由于手术方法的不同而导致手术后立即出现这种情况。较少

It appeals against a postoperative pain strongly immediately after an operation especially for less than 8 hours in many cases. It is suggested that the transfer system of NO-cyclic guanosine monophosphate (cGMP) has played the important role about anesthesia or painkilling. A possibility that an inhalation anesthetic will start consciousness hypersensitivity by low concentration is suggested. this consciousness--the descending control interception by the anesthetic drug in a spine is considered as one of the mechanisms about sensitive generating and its continuation. NOS inhibitor and 7-nitroindazole (7-NI) are HAROTAN by the research by the preceding year. MAC and Righting reflex ED50 It turned out that it influences to (RR). In the naked eye by operation, the damage on the peripheral nerve which is not visible is not avoided. Generating consciousness hypersensitivity not only according to an inhalation anesthetic but according to the obstacle of a peripheral nerve is known. Sharp pa … More in hypersensitivity by the obstacle of a peripheral nerve can also consider that the sharp pain control mechanism in a spine does not work effectively as a cause of the generating. the sharp pain according [we] to an inhalation anesthetic--the sharp pain according being sensitive to damage on a peripheral nerve--in order to investigate a sensitive common mechanism, a new sharp pain sensitive model was developed. The conventional Chung's and others method was the approach to the spinal nerves from a back side, and a possibility of having caused damage on a thin nerve in the operation process was high, and had caused sharp pain hypersensitivity in the operation opposite side. Even if consciousness hypersensitivity by the side of an operation half object happens in the approach from our abdominal side, it is small, and it turned out that it is advantageous in order to clarify descending control interception in a spine this time. the operation of the nerve damage by the approach from the back which we performed as a result of examining the data of the preceding year in detail--the conventional Chung's and others method, and control--consciousness--the big difference had arisen in the sensitive grade. Since this phenomenon was not produced in the approach from a hypersensitivity side, this operation might not necessarily be the model and same of Chung, the necessity of redoing the operation from the back again came out, and this fiscal year redid it. the result--control--consciousness--the difference has still arisen in the sensitive grade. It was suggested that the fundamental difference may have produced this immediately after an operation by the difference in the operation method. Less