Effect of night and shift work on glucose tolerance-circadian rhythm of glucose tolerance and insulin resistance

本研究的目的是探讨夜班和轮班工作对代谢综合征的标志物，如糖耐量和血脂的影响。对33名男性工人进行了调查。在每个班次后、白天、晚上和午夜进行采样。3个班次之间的平均血糖水平参数，如HbAlc、糖化白蛋白、1，5-脱水葡萄糖醇，在几周内没有任何显著差异。夜班和晚班的空腹胰岛素和HOMA-R显著高于白班.与白班相比，夜班和晚班的甘油三酯水平有升高的趋势，而与夜班和晚班相比，白班的LDL-胆固醇和游离脂肪酸水平升高.夜班和晚班血压明显高于白班.夜班和晚班的红细胞计数、红细胞压积、血红蛋白和血小板计数显著高于白班.白班、晚班和夜班的总能量摄入量无差异。然而，一些食物的摄入量，如蘑菇，土豆，大豆加工食品和绿色蔬菜往往是在夜间和晚班低于白班。夜班和晚班的能源消耗低于白班。

The aims of this study were to investigate the influences of night and shift work on the markers of metabolic syndrome, such as glucose tolerance, and serum lipids. Thirty-three male factory workers were investigated. The sampling were carried out after each shift, daytime, evening and midnight.1. There were not any significant differences in the parameters of mean blood glucose level during several weeks, such as HbAlc, glycoalbumin, 1,5-anhydroglycitol among three shifts. The fasting insulin and HOMA-R of night and evening shifts were significantly higher than those of daytime shift.2. The level of triglyceride tended to be higher at night shift and evening shifts compared with daytime shift, but LDL-cholesterol and free fatty acid were higher at daytime shift compared with night and evening shifts.3. The blood pressure at night and evening shifts were significantly higher than those at daytime shift.4. The red blood cell counts, hematcrit, hemoglobin and platelet count at night and evening shifts were significantly higher than those of daytime shift.5. Total energy intake was not different among daytime shift, evening shift and night shift. However, intake of some foods, such as mushroom, potatoes, processed foods of soybean and green vegetables tend to be lower at night and evening shifts compared with daytime shift.6. The energy consumption at night and evening shifts were lower than that at daytime shift.