Precise quantitative measurements of the mineral concentrations of compact bone for Japanese mandible by using spiral CT

本课题旨在利用螺旋CT对日本人下颌骨密质骨的骨密度进行精确的定量测量。为达到这一目的，本研究以羟基磷灰石和纯碳混合物为原料，制备了精密标准物质，并对多个微丸的强度和准确度进行了测试。对去Tsurumi大学口腔医院就诊的患者进行螺旋CT扫描，根据CT值与标准矿物质浓度(mg/mm~3)的线性回归，计算骨密度及其相关均值和标准差，最终检查人数分别为女性84例，男性71例，结果如下：1.日本人下颌骨密度：女性1.321±0.131 mg/mm~3，男性1.421±0.107 mg/mm~3。女性的BMD代际差异比较明显，而男性的代际差异不明显。日本女性下颌骨密度峰值出现在40岁左右。女性松质骨BMD存在明显的代际差异。这些结果支持了之前指出更年期影响的报告。

This project was planed to precise quantitative measurements of the bone mineral density (BMD) of compact bone for Japanese mandible by using spiral CT. To complete of this aim, the precise standard materials were prepared by making the pellets of hydroxyapatite and pure carbon mixture, and then tested plural pellets about the strength and the accuracy. After taking the spiral CT image of the patients who visit Tsurumi University Dental Hospital, the bone mineral density with related mean and standard deviation value were calculated according to the linear regression with the CT value and standard mineral concentration (mg/mm3).The final examined numbers of the patients were 84 female and 71 male, respectively.The following results were obtained ;1.The compact bone mineral density of Japanese mandible was female ; 1.321±0.131mg/mm3 and male ; 1.421 ± 0.107 mg/mm3.2. The generation difference of BMD in female was comparatively clear, although in male generation difference was not. The peak of compact bone mineral density of Japanese female mandible was shown in forties.3. The generation difference of the spongy bone BMD in female was considerably clear.4. These results support previous report which pointed out the influence of the menopause.