Regulation mechanism of biosynthesis, intracellular localization and degradation of membrane transporters

我们研究了烟草SCAMP的自噬降解调控以及细胞内定位和降解，SCAMP是一种被称为膜转运蛋白的护送蛋白，以及烟草中的蔗糖转运蛋白和拟南芥中的硼酸转运蛋白。通过对SCAMP的分析，我们发现了一种新的细胞内结构。我们还对蔗糖转运体和硼酸转运体降解的营养调控机制有了新的认识。

We investigated the regulation of autophagic degradation as well as the intracellular localization and degradation of tobacco SCAMP, which is known as an escort protein of membrane transporters, as well as sucrose transporters from tobacco and a borate transporter from Arabidopsis. We found a novel intracellular structure through the analysis of the SCAMP. We also got novel mechanistic insights on the nutritional regulation of the degradation of both sucrose transporters and the borate transporter.