New Imaging Agents for Neuronal Nicotinic Receptors

医学成像技术的最新进展，如正电子发射断层扫描（PET）和单光子发射计算机断层扫描（SPECT），从根本上改善了各种疾病的诊断和治疗。这个项目的目的是发现新的放射性配体，选择性地结合神经元烟碱乙酰胆碱受体。这些配体在阿尔茨海默病等神经退行性疾病的成像、诊断和研究方面具有很大的潜力。

Recent advances in medical imaging technology such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) have radically improved the diagnosis and treatment of a wide range of diseases. The aim of this project is to discover novel radio-ligands that selectively bind to neuronal nicotinic acetylcholine receptors. These ligands will have great potential for the imaging, diagnosis and study of neurodegenerative diseases such as Alzheimer's disease.