The first generation of single entity measurement tools for analysis

第一代用于分析的单一实体测量工具：该奖学金项目旨在开发一种新型的诊断设备，用于测量单个分子或单个细胞。这种测量方法试图通过识别样本中的异质性和罕见事件，而不是现有工具提供的平均信息，来彻底改变分析方法。对于单分子器件，响应的异质性使得开发多路复用，无需校准的传感器成为可能。该项目的成果有望带来全新的测量思维、生物学异质性的新知识以及新型商业化传感器的潜力。预计这不仅在生物学发现方面很重要，而且在为环境监测、疾病预测、个性化医疗或药物发现等应用提供更强大的传感器方面也很重要。

The first generation of single entity measurement tools for analysis: This fellowship project aims to develop a new type of diagnostic device that measures single molecules or single cells. Such measurements seek to revolutionise analysis by allowing heterogeneity and rare events in samples to be identified, rather than the average information provided by existing tools. With single molecule devices, the heterogeneity in response enables the development of multiplexed, calibration free sensors. The outcomes of the project are hoped to be completely new thinking on performing measurements, new knowledge regarding heterogeneity in biology and the potential for novel commercialised sensors. It is expected that this will be important not only in biological discovery, but also in providing far more robust sensors for applications such as environmental monitoring, disease prediction, personalised medicine or drug discovery.