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How electric fields can facilitate reversible protein binding to surfaces

How electric fields can facilitate reversible protein binding to surfaces
电场如何促进可逆蛋白质与表面的结合
批准号:
DP220103024
负责人:
Prof John Gooding
金额:
$31.24万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2022
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2022-01-01 至 2025-05-31

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中文摘要
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英文摘要
The aim of this project is to develop the first biosensors that prevent nonspecific protein adsorption and allow reversible protein binding. The project expects to achieve this using a combination of novel surface chemistry and pulsed electric fields that dynamically change a sensing interface. The impact of electric fields on the binding of proteins to this interface will be followed using a novel single molecule fluorescence microscope previously developed that can locate the position of proteins with 2 nanometer resolution. The expected outcomes of this project is a class of biosensor that can continuously monitor protein biomarkers for wearable sensors that provide information on a user’s wellness and nutrition.
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Bioinks that Advance 3D bioprinting of cells to the 4th dimension
  • 批准号:
    LP210200868
  • 项目类别:
    Linkage Projects
  • 资助金额:
    $35.98万
  • 财政年份:
    2023
  • 负责人:
    Prof John Gooding
  • 依托单位:
Understanding how nanoconfinement can enhance electrochemical reactions
  • 批准号:
    DP210102698
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $27.41万
  • 财政年份:
    2021
  • 负责人:
    Prof John Gooding
  • 依托单位:
Bioinks for the 3D printing of cells made from off-the-shelf components
  • 批准号:
    LP170100623
  • 项目类别:
    Linkage Projects
  • 资助金额:
    $29.15万
  • 财政年份:
    2018
  • 负责人:
    Prof John Gooding
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Precision nanomedicine-based diagnostics and therapeutics for refractory malignancies
  • 批准号:
    nhmrc : GNT1091261
  • 项目类别:
    Programs
  • 资助金额:
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  • 财政年份:
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  • 负责人:
    Prof John Gooding
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国内基金
海外基金
Probing matter-antimatter asymmetry with the muon electric dipole moment
  • 批准号:
    --
  • 项目类别:
    --
  • 资助金额:
    30万元
  • 批准年份:
    2020
  • 负责人:
    Kim Siang Khaw
  • 依托单位:
电场对血管发生的调控作用及其信号转导通路的研究
基于电刺激的动物运动行为控制方法研究
  • 批准号:
    60375026
  • 项目类别:
    面上项目
  • 资助金额:
    23.0万元
  • 批准年份:
    2003
  • 负责人:
    原魁
  • 依托单位: