Transplantation of cultured mucosal epithelium : an experimental and clinical study

1975年H.Green等人制备的体外培养上皮被广泛认为是皮肤缺损移植的有用材料。在整形和重建外科领域，许多临床报告已经证明了成功培养的培养上皮的实用性。此外，一些作者已经报道了培养上皮移植的成功应用。近年来，一些研究也探讨了培养口腔黏膜上皮在颌面外科移植中的临床应用。我们使用的移植物是先前冷冻并在145℃下长期保存的培养移植物。我科研究了一种新的治疗方式，即保存自体和异体培养的上皮，并将其自体和异体移植到皮肤或粘膜缺损上。

Cultured epithelium fabricated by H.Green et al.in 1975 have been widely acknowledged to be useful materials for the transplantation on skin defects. In the field of plastic and reconstructive surgery, many clinical reports have demonstrated the utility of cultured epithelium which have been sucessfully cultured. Moreover, several authors have reported the application of cultured epithelial allografting successfully. Recently, some researches have also discussed about the clinical utility of cultured oral mucosal epithelium for grafting in maxillofacial surgery. We utilized cultured grafts that had been previously frozen and maintained at-145ﾟC for a long time.Our department has been investigated a new therapeutic modality, in which autologous and allogenous cultured epithelium are preserved and auto- and allo- grafted to skin or mucosal defects.