Creation of a super-resolution map of the bacterial cytokinesis machinery

细胞分裂是生命必不可少的基本过程。然而，我们在分子水平上对这一过程的理解是有限的，主要是因为无法以足够的分辨率可视化这些微小细胞内分裂机制的不同组成部分。为了克服这一障碍，利用成像和分子技术的最新进展以及创新工程，该项目旨在以前所未有的分辨率创建细菌细胞内分裂机制的空间和时间地图。预期的结果是关于细菌分裂机制的新知识和生物成像技术的进步，为广泛领域的应用提供信息。

Cell division is a fundamental process essential for life. Yet our understanding of this process on a molecular level is limited, mostly hampered by the inability to visualize the different components of the division machinery inside these tiny cells with adequate resolution. To overcome this barrier, capitalizing on recent advancements in imaging and molecular technologies combined with innovative engineering, this project aims to create a spatial and temporal map of the division machinery inside bacterial cells at unprecedented resolution. The expected outcomes are new knowledge on the mechanism of bacterial division and technological advances in biological imaging, informing applications in a wide variety of sectors.