Super-resolution platform to accelerate biological and molecular research

加速生物和分子研究的超分辨率平台

• 批准号: LE240100134
• 负责人: Prof David Fairlie
• 金额: $ 53.09万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE240100134
• 关键词: Super; resolution; platform; accelerate; biological

This application aims to establish a new molecular analysis platform integrating a microfluid capillary electrophoresis interface directly to a mass spectrometer with advanced data scanning technology. This enables label-free detection, quantitation and characterisation of intact proteins, lipids and metabolites with unprecedented sensitivity, resolution and throughput. It will enhance ARC projects spanning natural product discovery, biotechnology, agriculture, and animal, plant and marine biology, as well as single-cell proteomics, lipidomics and metabolomics. It will ensure Australia remains at the forefront of molecular and biological research and create new training and collaborative opportunities both nationally and internationally.

本应用程序旨在建立一个新的分子分析平台，将微流体毛细管电泳接口直接集成到具有先进数据扫描技术的质谱仪上。这使得完整的蛋白质，脂质和代谢物具有前所未有的灵敏度，分辨率和吞吐量的无标签检测，定量和表征。它将加强ARC的项目，包括天然产品发现、生物技术、农业、动物、植物和海洋生物学，以及单细胞蛋白质组学、脂质组学和代谢组学。它将确保澳大利亚保持在分子和生物学研究的前沿，并在国内和国际上创造新的培训和合作机会。