Centrifugal type artificial heart of high durability using a magnetic bearing

为心脏病患者开发了可植入的心脏辅助装置和一次性血泵1)可植入的心脏辅助装置磁悬浮(Maglev)离心式血泵(CBP)旨在用作心脏辅助装置，需要高度耐用和可靠，可长期使用且不会出现任何机械故障。此外，磁悬浮CBPS应该足够小，可以植入不同大小和体重的患者体内。我们开发了一种紧凑型磁悬浮CBP，采用两自由度可控磁轴承，磁悬浮叶轮由内部无刷直流(DC)电机直接驱动。磁悬浮轴承主动控制叶轮的径向运动，并利用嵌入叶轮中的永磁体被动支持轴向和角向运动。磁悬浮CBP的总体尺寸为直径65 mm，高度40 mm。再抽6 L/分钟…的总电耗和泵效大于105 mm Hg的头部压力分别为6.5W和21%。比较了磁悬浮CBP和Medtronic Biomedicus BPX-80的溶血特性，证明了磁悬浮CBP的优越性。2)研制了一次性体外循环用一次性血泵。该泵的设计目的是消除叶轮的机械接触，实现简单的一次性机构，并减少电机和磁轴承对血液的加热效应。一次性泵头预充量为23毫升，由顶壳、底壳、叶轮和直径50 mm的转子组成。该泵可以提供300毫米汞柱以上的功率，而L的功率为5毫米汞柱/分钟。标化溶血指数为0.0025±0.0005克/100L，5 L/分钟，250毫米汞柱。这是生物泵BPX-80(美国美敦力公司)的七分之一。0.0170±0.0096 g/100L。这些结果表明，MedTech Dispao实现了高泵性能和低血液创伤。较少

Implantable ventricular assist devises and disposable blood pumps have been developed for heart disease patients.1)Implantable ventricular assist deviseA magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have developed a compact maglev CBP employing a two-degree-of-freedom controlled magnetic bearing, with a magnetically suspended impeller directly driven by an internal brushless direct current (DC) motor. The magnetic bearing actively controls the radial motion of the impeller and passively supports axial and angular motions using a permanent magnet embedded in the impeller. The overall dimensions of the maglev CBP are 65 mm in diameter and 40 mm in height. The total power consumption and pump efficiency for pumping 6 L/min again … More st a head pressure of 105 mm Hg were 6.5 W and 21%, respectively. The hemolytic characteristics of the maglev CBP were compared with those of the Medtronic Biomedicus BPX-80, which demonstrated the superiority of the maglev CBP.2)Disposable blood pumpA magnetically levitated (MagLev) centrifugal blood pump (MedTech Dispo) has been developed for a disposable extracorporeal system. The pump design is aimed at eliminating mechanical contact of an impeller, realization of a simple disposable mechanism, and reduction of the heating effect on blood due to a motor and a magnetic bearing. The disposable pump head with priming volume of 23 mL consists of top and bottom housings, the impeller and the rotor with diameter of 50 mm. The pump can provide more than 300 mmHg against 5 L/min. Normalized index of hemolysis (NIH) of the MedTech Dispo is 0.0025 ± 0.0005 g/100L at 5 L/min against 250 mmHg. This is one seventh of that of Bio Pump BPX-80 (Medtronic Inc, U.S.A.) of 0.0170 ± 0.0096 g/100L. These results show that the MedTech Dispo realizes high pump performance and low blood trauma. Less