Development of self healing materials with remineralization(Bioglass for dental materials)

本研究的一个发现是晶体形成（直径约10 μm）是一些氟化胶粘剂树脂的共同特征，这些树脂被牙齿和固化材料之间的标准化界面间隙分隔开。在生物玻璃（Na_2-CaO-SiO_2-P_2O_5）粘接树脂中，经过几个月的水储存，也发现了这种晶体生长。生物玻璃的加入完全降低了树脂胶粘剂的力学性能。粘合剂中生物玻璃添加量的减少阻止了材料机械性能的降低，但它减少了再矿化离子释放量。由于生物玻璃与水的同步反应，晶体生长可能引起力学性能的降低。理论上，有一种可能性可以增加每单位生物玻璃的表面积，从而使它们更活跃。未来的方法可能是简单地减小玻璃颗粒尺寸（纳米级生物玻璃），从而增加玻璃和周围液体的离子交换表面，防止力学性能下降，用于临床应用。

A finding in this study was that crystal formation (approximately 10 μm in diameter) was a common feature of some fluoridated adhesive resins, where were separated by a standardized interfacial gap between teeth and cured materials. This crystal growth was also found in bioglass (Na_2-CaO-SiO_2-P_2O_5) -containing adhesive resins after several months of water storage. The mechanical properties of resin adhesives are completely reduced by bioglass addition. The decreasing amount of bioglass addition for adhesives prevents a reduction of mechanical property of materials but it reduces an amount of ion releasing for remineralization. The reduction of mechanical property may induced by crystal growth formation due to simultaneous response between bioglass and water. In theory, there are one possibility for increasing the surface area of bioglass per unit, and thus making them more active. An future approach may be simply to decrease glass particle size (nano-sized bioglass), and thus increase the ion exchange surface of glass and surrounding liquid, and prevent mechanical property decreasing for clinical use.