Roles of odorant receptor signaling in axonal projection of olfactory sensory neurons
Roles of odorant receptor signaling in axonal projection of olfactory sensory neurons
批准号:
20509002
负责人:
IMAI Takeshi
金额:
$2.49万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
在本研究中,我们发现气味受体通过Gs和Golf控制嗅觉感觉神经元的轴突投射,每个受体控制轴突引导的不同阶段。我们还对小鼠嗅觉地图形成的靶前轴突分类进行了分析,发现靶前轴突分类在根据轴突所表达的引导分子的相对水平建立地形图顺序方面起着重要作用。
英文摘要
In this study, we found that odorant receptors control axonal projection of olfactory sensory neurons via Gs and Golf, each controlling distinct phase of axon guidance. We also analyzed the pre-target axon sorting for olfactory map formation in mice, and found that pre-target axon sorting plays an important role in establishing the topographic order based on the relative levels of guidance molecules expressed by axons.
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DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
Roles of Axon-Axon Interactions in the Formation and Maintenance of the Mouse Olfactory Map
轴突-轴突相互作用在小鼠嗅觉图的形成和维持中的作用
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[今井猛, Yamazaki T, Sakano H]
通讯作者:
Sakano H
DOI:
10.1007/400_2008_3
发表时间:
2009-01-01
期刊:
CHEMOSENSORY SYSTEMS IN MAMMALS, FISHES, AND INSECTS
影响因子:
--
作者:
[Imai, T., Sakano, H.]
通讯作者:
Sakano, H.
DOI:
10.1101/cshperspect.a001776
发表时间:
2010-08-01
期刊:
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
影响因子:
7.2
作者:
[Imai, Takeshi, Sakano, Hitoshi, Vosshall, Leslie B.]
通讯作者:
Vosshall, Leslie B.
Axon-axon interaction in the neural map formation.
神经图形成中的轴突-轴突相互作用。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Imai T, Yamazaki T, Sakano H]
通讯作者:
Sakano H
共 13 条
Amiloride promotes oligodendrocyte survival and remyelination after spinal cord injury in rats
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批准号:26861215
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.16万
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财政年份:2014
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负责人:IMAI Takeshi
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依托单位:
A research on modeling Diabetes Disease Progression based on Causal Chain Ontology
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批准号:23790561
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2011
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负责人:IMAI Takeshi
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依托单位:
Automated Disease Name Classification into International Classification of Diseases based on a Medical Ontology
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批准号:19700128
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.32万
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财政年份:2007
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负责人:IMAI Takeshi
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依托单位:
海外基金