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Immune modulatory functions of mature mast cells

Immune modulatory functions of mature mast cells
成熟肥大细胞的免疫调节功能
批准号:
21790100
负责人:
TANAKA Satoshi
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

项目摘要

项目成果

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相关文献

中文摘要
翻译
肥大细胞是一种免疫细胞,广泛分布于全身各处,并且根据它们驻留的位置而具有不同的特性。本研究采用一种新的成熟肥大细胞培养模型,探讨了成熟肥大细胞的功能作用。成熟的肥大细胞被发现获得的能力,以响应非IgE刺激,而他们表现出较低的反应IgE依赖性抗原刺激。这些发现表明,组织成熟肥大细胞的适当的培养模型,应需要澄清其免疫调节功能。
英文摘要
Mast cells are a kind of immune cells, which are widely distributed throughout the body, and are different in character depending on where they are resident. The functional roles of mature mast cells were investigated in this study using a novel culture model for mature mast cells. Mature mast cells were found to acquire the ability to respond to non-IgE stimuli, whereas they exhibited lower responses to IgE-dependent antigen stimulation. These findings suggest that appropriate culture models for tissue mature mast cells should be required for clarification of their immune modulatory functions.
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会议论文
Enhancement of IgM production in B cells by the extract of red bell pepper.
红甜椒提取物增强 B 细胞中 IgM 的产生。
DOI: --
发表时间: 2010
期刊: J.Health Sci. 56
影响因子: --
作者: [Goto, T., Sarker, M.M.R., Zhong, M., Tanaka, S., Gohda, E.]
通讯作者: E.
DOI: 10.2183/pjab.86.848
发表时间: 2010
期刊: Proceedings of the Japan Academy. Series B, Physical and biological sciences
影响因子: --
作者: [Ichikawa A, Sugimoto Y, Tanaka S]
通讯作者: Tanaka S
Biomedical Aspects of Histamine : Current Perspectives (ed. Khardori, N., Shahid, M., Khan, RA, Tripathi, T) Springer
组胺的生物医学方面:当前观点(编者:Khardori, N.、Shahid, M.、Khan, RA、Tripathi, T)Springer
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Tanaka, S., Ichikawa, A.]
通讯作者: A.
CD44を介したマウス組織結合型マスト細胞の増殖制御
CD44介导的小鼠组织结合肥大细胞的增殖控制
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [田中智之, 高野裕嗣, 木全弘治, 中山和久, 杉本幸彦, 市川厚]
通讯作者: 市川厚
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