Quantitative Diagnosis Method of Hepatic Disease based on AcousticCharacteristics of Tissues

在这项研究中，我们开发了一种新的定量诊断技术来估计肝炎肝纤维化的程度，使用的模型表达了来自肝纤维化组织的超声回波的幅度分布。在该模型中，幅值分布由正常组织、纤维化组织、结节组织三种瑞利分布组成。通过计算机模拟、组织模型和临床数据的分析，证明该定量技术对肝炎的定量诊断是有效的。

In this study, we developed a new quantitative diagnosis technique to estimate degree of fibrosis of the hepatitis liver using a model that expresses the amplitude distribution of the ultrasonic echo from a fibrotic liver tissue. In the model, the amplitude distribution is composed by three kinds of Rayleigh distribution corresponding to normal, fibrosis, nodule tissues. Using computer simulation, the tissue phantom, the clinical data, it was shown that the new quantitative technique is valid for the quantitative diagnosis of liver hepatitis.