Significance of feeding regulation of peptides in eating abnormality in digestive diseases

幽门螺杆菌是一种感染了一半以上日本人口的细菌，与慢性胃炎、消化性溃疡和胃癌有关。我们对幽门螺杆菌感染与各种喂养和代谢调节因子的关系进行了临床研究。该结果提出了一种可能性，即幽门螺杆菌感染通过改变血浆中调节摄食行为的胃饥饿素和调节代谢状态的脂联素水平来影响宿主的营养状况。

Helicobacter pylori is a bacterium that has infected more than half of the Japanese population and is associated with chronic gastritis, peptic ulcer, and gastric cancer. We conducted a clinical study on the association between Helicobacter pylori infection and various feeding and metabolic regulating factors. The result raises the possibility that Helicobacter pylori infection affects the host’s nutritional status through changes in the plasma levels of ghrelin, which regulates feeding behavior, and adiponectin, which regulates metabolic status.