Development of new synthetic reactions based on novel acid catalysts

合成有机化学在开发功能化学品中发挥着重要作用。在本研究中，为了提高化学合成的效率，我们成功地开发出了含有C-H酸官能团的高效酸催化剂。在某些使用硅烯醇酸盐的反应中，碳酸可以作为最有效的催化剂之一。此外，我们还发现In(OTf)3很好地催化了基于异氰基的新型多组分反应。

Synthetic organic chemistry plays an important role to develop functional chemicals. In this research, to improve the efficiency of chemical synthesis, we successfully developed highly effective acid catalyst containing C-H acid functionality. The carbon acid can be used as one of the most effective catalysts in some reactions using silicon enolates. Furthermore, we found that In(OTf)3 nicely catalyzes novel isocyanide-based multi component reactions.