Increasing the size of the specific pathogen free Indian rhesus macaques colony at the Southwest National Primate Research Center for AIDS, COVID-19 and other infectious diseases research

抽象的。 无特定病原体(SPF)印度原产猕猴(恒河猴)是 传染病研究，包括艾滋病毒/艾滋病、结核病、流感、莱姆病，现在是新冠肺炎。那里有 在过去的几十年里，这种动物在全国范围内严重短缺，这是很好的- 有记录在案。与新冠肺炎疫情相关的多种原因使这种情况变得更加困难。进口商品 来自亚洲的这些动物已经停止，生物医药公司已经使用了大量的这些动物 在过去的一年。一些动物也被虚拟实验室的调查人员用于新冠肺炎研究 七个国家灵长类动物研究中心中的每一个。因此，迫切需要 增加SPF印度血统恒河猴的供应。此应用程序建议增加 在西南国家灵长类动物研究中心(SNPRC)生产这些动物。

Abstract. Specific pathogen free (SPF) Indian origin Macaca mulatta (rhesus macaques) are the premier model for infectious disease research including HIV/AIDS, TB, influenza, Lyme disease, and now COVID-19. There has been an acute nationwide shortage of these animals over the past couple of decades, which has been well- documented. Multiple reasons related to the COVID-19 pandemic have made this situation more difficult. Imports of these animals from Asia have stopped, and biomedical corporates have used large number of these animals in the past year. A number of animals have also been used in COVID-19 research by investigators at virtually each of the seven National Primate Research Centers (NPRCs). Hence, there is an acute, urgent need to increase the availability of SPF Indian origin rhesus macaques. This application proposes to increase the production of these animals at the Southwest National Primate Research Center (SNPRC).