Shared Resource Management

共享资源管理--项目摘要 弗吉尼亚大学癌症中心(UVACC)共享资源的使命是提供高质量的、 为UVACC成员提供符合UVACC目标的增值支持。该项目的管理 共享资源的重点是有效管理共享资源；确保共享的 资源满足UVACC成员的科学需求；规划未来的方向和需求 用于共享资源支持的UVACC。 在上一次更新UVACC时，提交了七个共享资源，其中包括高级显微镜 设施(AMF)(评分优秀到优秀)，疾病核心动物模型(AMDC)(评分优秀)， 生物信息学核心(BIC)(得分非常好到极好)，生物分子分析设施(BAF)(得分 优秀)，生物信息库和组织研究设施(BTRF)(得分非常好到非常优秀)， 生物统计学共享资源(BSR)(从优秀到优秀)和流式细胞仪核心(FCC) (得分从优秀到杰出)。在目前提交的材料中，UVACC还提出了七个共享 资源。然而，应UVACC项目负责人的要求，并根据建议 根据上一次的审查和外部审查，UVACC重新组织和改进了 疾病核心将包括额外的方案和技术，用于研究癌症和 并将核心更名为分子和免疫翻译科学核心(MITS)。 鉴于大多数生物信息学工作都与支持数据密集型平台有关 在生物活性因子(如DNA和RNA测序、蛋白质组学和代谢组学)中，BIC现在是 嵌入在生物滤池中。支持癌症控制和人口健康计划的研究人员 (CPH)，我们增加了一个共享资源，即人口健康和癌症结果核心(PHCOC)。 这些结构变化，以及对每个共享资源的重点改进 上一次审查的建议，将UVACC共享资源定位为提供卓越的专业知识， 支持和教育会员对癌症研究的追求，使之与UVACC的使命保持一致。

SHARED RESOURCES MANAGEMENT – PROJECT SUMMARY The mission of the University of Virginia Cancer Center (UVACC) Shared Resources is to provide high quality, value-added support for UVACC Members as aligned with the goals of the UVACC. The management of the Shared Resources is focused on effectively managing the Shared Resources; ensuring that the Shared Resources meet the scientific needs of the UVACC Members; and planning for future directions and needs of the UVACC for Shared Resource support. At the last renewal of the UVACC, seven Shared Resources were submitted including Advanced Microscopy Facility (AMF) (Scored Outstanding to Excellent), Animal Models of Disease Core (AMDC) (Scored Excellent), Bioinformatics Core (BIC) (Scored Very Good to Excellent), Biomolecular Analysis Facility (BAF) (Scored Outstanding), Biorepository and Tissue Research Facility (BTRF) (Scored Very Good to Excellent), Biostatistics Shared Resource (BSR) (Scored Outstanding to Excellent), and Flow Cytometry Core (FCC) (Scored Excellent to Outstanding). In the current submission, the UVACC also proposes seven Shared Resources. However, in response to the requests from UVACC Program Leaders, and based on suggestions from the last review and external reviewers, the UVACC reorganized and enhanced the Animal Models of Disease Core to include additional protocols and technology for studying immune response in cancer and cancer therapy and renamed the core the Molecular and Immunological Translational Sciences Core (MITS). Given that most of the bioinformatics efforts are in association with support of the data-intensive platforms present in the BAF (such as DNA and RNA sequencing, proteomics and metabolomics) the BIC is now embedded within the BAF. To support researchers in the Cancer Control and Population Health Program (CPH), we have added one Shared Resource, the Population Health and Cancer Outcome Core (PHCOC). These changes in structure, along with focused improvements to the Shared Resources per the recommendations of the last review, position the UVACC Shared Resources to provide exceptional expertise, support, and education for Members' pursuit of cancer research as aligned with the mission of the UVACC.