PRIDE-Functional and Translational Genomics of Blood Disorders

摘要 缺乏多样性仍然是生物医学和行为科学研究计划的一个重大挑战 以及美国学术中心的师资组成。美国国家心肺血液研究所（NHLBI） 2006年夏季学院增加多样性计划（SIPID）。因此，计划增加 健康相关研究中个体的多样性-功能和翻译基因组学 血液疾病（PRIDE-FTG）在奥古斯塔大学成立。通过PRIDE-FTG计划，我们 为76名任职人数不足的少数族裔初级教员调查员提供了辅导培训。学员了解到 在连续两个夏季学院的实践台研究和grananimousskills。程序 评估有助于实现我们的主要目标，即帮助学员提交国家卫生研究院或同等机构的报告 在项目完成后两年内申请资助，NIH资助率为41.7%， 首席调查员我们建议在PRIDE-FTG的下一次迭代中继续这种指导式培训， 扩展到包括几个创新的组成部分和与肥胖健康差异的合作- PRIDE计划汇集联邦资源。我们将测试一个假设，即一个指导培训计划，以建立 研究和赠款写作技能将提高URM和残疾人教师的能力，进行血液 疾病研究，以获得校外资助和过渡到独立的研究事业。四个目标将 目标：1。在奥古斯塔大学进行创新暑期研究所1（组件1）。 入读PRIDE-FTG计划的学员将参加多学科课程，包括 开展实地研究培训和赠款发放活动，以制定供资战略。AIM 2.支持 小型研究项目资助倡议（组成部分4）。与骄傲指导委员会合作 和NHLBI计划工作人员，PRIDE-FTG计划将资助重点试点项目，以支持竞争性赠款 关于血液病研究的建议。AIM 3.促进指导和网络活动 （构成部分2）。导师委员会由一名学员、一名PRIDE研究导师和一名家庭成员组成。 将设立机构导师。同侪指导小组将在同一批人中启动，以促进研究 协作该计划将支持年中访问导师的机构和出席 全联盟范围的骄傲年会目标4：开展创新暑期研究所2（组成部分3）。 学员将返回奥古斯塔大学完成一对一的补助金审查，以实现以下主要目标： PRIDE计划提交NIH或同等资助申请并参与其他研究 经验PRIDE-FTG计划支持的指导培训将影响 代表性不足和残疾科学家实现成功的生物医学研究事业。

Abstract The lack of diversity remains a significant challenge in biomedical and behavioral science research programs and faculty composition in US academic centers. The National Heart, Lung, and Blood Institute (NHLBI) funded the Summer Institute Program to Increase Diversity (SIPID) in 2006. Subsequently, the Program to Increase Diversity Among Individuals Engaged in Health-Related Research-Functional and Translational Genomics of Blood Disorders (PRIDE-FTG) was established at Augusta University. Through the PRIDE-FTG program, we provided mentored training for 76 underrepresented minority junior faculty investigators. Mentees learned hands-on bench research and grantsmanship skills during two consecutive Summer Institutes. Program evaluation supports the achievement of our primary goal of aiding mentees to submit an NIH or equivalent grant application within two years of program completion, demonstrated by a 41.7% NIH grant-funding rate as principal investigator. We propose to continue this mentored training with the next iteration of PRIDE-FTG, expanded to include several innovative components and collaboration with the Obesity Health Disparities- PRIDE program to pool federal resources. We will test the hypothesis that a mentored training program to build research and grant-writing skills will increase the ability of URM and disabled faculty, conducting blood disorders research to obtain extramural funding and transition to independent research careers. Four aims will be accomplished: AIM 1. Conduct Innovative Summer Institute 1 at Augusta University (Component 1). Mentees matriculating into the PRIDE-FTG program will participate in a multidisciplinary curriculum including hands-on-bench research training and grant-writing activities to develop funding strategies. AIM 2. Support Small Research Project Funding Initiative (Component 4). In collaboration with the PRIDE Steering Committee and NHLBI program staff, the PRIDE-FTG program will fund focused pilot projects to support competitive grant proposals addressing blood disorders research. AIM 3. Facilitate Mentoring and Networking Activities (Component 2). Mentorship Committees comprised of a mentee, a PRIDE research mentor and home institution mentor will be established. Peer-mentorship teams will launch within cohorts to promote research collaboration. The program will support a mid-year visit to the mentor’s institution and attendance at the consortium-wide PRIDE annual meeting. AIM 4: Conduct Innovative Summer Institute 2 (Component 3). Mentees will return to Augusta University to complete a one-on-one grant review to meet the primary goal of the PRIDE program to submit an NIH or equivalent grant application and participate in additional research experiences. The mentored training supported by the PRIDE-FTG program will influence the number of underrepresented and disabled scientists achieving successful biomedical research careers.